Samel N - Search Results

1

A conserved π-cation and an electrostatic bridge are essential for 11R-lipoxygenase catalysis and structural stability.

Eek P, Piht MA, Rätsep M, Freiberg A, Järving I, Samel N. Eek P, et al. Among authors: samel n. Biochim Biophys Acta. 2015 Oct;1851(10):1377-82. doi: 10.1016/j.bbalip.2015.07.007. Epub 2015 Jul 26. Biochim Biophys Acta. 2015. PMID: 26215075

2

Identification and characterization of an arachidonate 11R-lipoxygenase.

Mortimer M, Järving R, Brash AR, Samel N, Järving I. Mortimer M, et al. Among authors: samel n. Arch Biochem Biophys. 2006 Jan 1;445(1):147-55. doi: 10.1016/j.abb.2005.10.023. Epub 2005 Nov 15. Arch Biochem Biophys. 2006. PMID: 16321357

3

Identification of a functional allene oxide synthase-lipoxygenase fusion protein in the soft coral Gersemia fruticosa suggests the generality of this pathway in octocorals.

Lõhelaid H, Järving R, Valmsen K, Varvas K, Kreen M, Järving I, Samel N. Lõhelaid H, et al. Among authors: samel n. Biochim Biophys Acta. 2008 Feb;1780(2):315-21. doi: 10.1016/j.bbagen.2007.10.010. Epub 2007 Oct 22. Biochim Biophys Acta. 2008. PMID: 17996204

4

Structure of a calcium-dependent 11R-lipoxygenase suggests a mechanism for Ca2+ regulation.

Eek P, Järving R, Järving I, Gilbert NC, Newcomer ME, Samel N. Eek P, et al. Among authors: samel n. J Biol Chem. 2012 Jun 22;287(26):22377-86. doi: 10.1074/jbc.M112.343285. Epub 2012 May 9. J Biol Chem. 2012. PMID: 22573333 Free PMC article.

5

A PDZ-like domain mediates the dimerization of 11R-lipoxygenase.

Eek P, Põldemaa K, Kasvandik S, Järving I, Samel N. Eek P, et al. Among authors: samel n. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Oct;1862(10 Pt A):1121-1128. doi: 10.1016/j.bbalip.2017.07.012. Epub 2017 Aug 1. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28774821

6

Activation of 11R-lipoxygenase is fully Ca(2+)-dependent and controlled by the phospholipid composition of the target membrane.

Järving R, Lõokene A, Kurg R, Siimon L, Järving I, Samel N. Järving R, et al. Among authors: samel n. Biochemistry. 2012 Apr 17;51(15):3310-20. doi: 10.1021/bi201690z. Epub 2012 Apr 3. Biochemistry. 2012. PMID: 22448896

7

Structural and catalytic insights into the algal prostaglandin H synthase reveal atypical features of the first non-animal cyclooxygenase.

Varvas K, Kasvandik S, Hansen K, Järving I, Morell I, Samel N. Varvas K, et al. Among authors: samel n. Biochim Biophys Acta. 2013 Apr;1831(4):863-71. doi: 10.1016/j.bbalip.2012.11.010. Epub 2012 Dec 5. Biochim Biophys Acta. 2013. PMID: 23220097

8

Gly188Arg substitution eliminates substrate inhibition in arachidonate 11R-lipoxygenase.

Põldemaa K, Lipp M, Järving I, Samel N, Eek P. Põldemaa K, et al. Among authors: samel n. Biochem Biophys Res Commun. 2019 Oct 29;519(1):81-85. doi: 10.1016/j.bbrc.2019.08.132. Epub 2019 Aug 30. Biochem Biophys Res Commun. 2019. PMID: 31477267

9

Novel membrane-associated prostaglandin E synthase-2 from crustacean arthropods.

Hansen K, Varvas K, Järving I, Samel N. Hansen K, et al. Among authors: samel n. Comp Biochem Physiol B Biochem Mol Biol. 2014 Aug;174:45-52. doi: 10.1016/j.cbpb.2014.05.004. Epub 2014 Jun 16. Comp Biochem Physiol B Biochem Mol Biol. 2014. PMID: 24947207

10

Structural and functional comparison of 15S- and 15R-specific cyclooxygenases from the coral Plexaura homomalla.

Valmsen K, Boeglin WE, Järving I, Schneider C, Varvas K, Brash AR, Samel N. Valmsen K, et al. Among authors: samel n. Eur J Biochem. 2004 Sep;271(17):3533-8. doi: 10.1111/j.0014-2956.2004.04289.x. Eur J Biochem. 2004. PMID: 15317588 Free article.

., Boeglin, W.E., Varvas, K., Koljak, R., Pehk, T., Brash, A.R. & Samel, N. (2001) Proc. Natl. Acad. Sci. USA98, 7700]. Here we describe the cloning and characterization of a closely related COX protein (97% amino acid sequence identity) from the S-variety of P. …

., Boeglin, W.E., Varvas, K., Koljak, R., Pehk, T., Brash, A.R. & Samel, N. (2001) Proc. Natl. Acad. Sci. USA98, 7700]. He …

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