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Page 1
Acid-sensing ion channel 1a blockade reduces myocardial injury in rodent models of myocardial infarction.
Redd MA, Yoshikawa Y, Khan N, Waqar M, Saez NJ, Outhwaite JE, Russell JS, Hanna AD, Chiu HS, Er SY, Butcher NJ, Mardon K, Fraser JF, Smythe ML, Rash LD, Thomas WG, King GF, Reichelt ME, Palpant NJ. Redd MA, et al. Among authors: saez nj. Eur Heart J. 2024 May 7;45(17):1571-1574. doi: 10.1093/eurheartj/ehad793. Eur Heart J. 2024. PMID: 38095341 No abstract available.
A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.
Eagles DA, Saez NJ, Krishnarjuna B, Bradford JJ, Chin YK, Starobova H, Mueller A, Reichelt ME, Undheim EAB, Norton RS, Thomas WG, Vetter I, King GF, Robinson SD. Eagles DA, et al. Among authors: saez nj. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2112630119. doi: 10.1073/pnas.2112630119. Proc Natl Acad Sci U S A. 2022. PMID: 35131940 Free PMC article.
Strategies for Heterologous Expression, Synthesis, and Purification of Animal Venom Toxins.
Rivera-de-Torre E, Rimbault C, Jenkins TP, Sørensen CV, Damsbo A, Saez NJ, Duhoo Y, Hackney CM, Ellgaard L, Laustsen AH. Rivera-de-Torre E, et al. Among authors: saez nj. Front Bioeng Biotechnol. 2022 Jan 20;9:811905. doi: 10.3389/fbioe.2021.811905. eCollection 2021. Front Bioeng Biotechnol. 2022. PMID: 35127675 Free PMC article. Review.
Total Synthesis of the Spider-Venom Peptide Hi1a.
Duggan NM, Saez NJ, Clayton D, Budusan E, Watson EE, Tucker IJ, Rash LD, King GF, Payne RJ. Duggan NM, et al. Among authors: saez nj. Org Lett. 2021 Nov 5;23(21):8375-8379. doi: 10.1021/acs.orglett.1c03112. Epub 2021 Oct 11. Org Lett. 2021. PMID: 34632783
Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury.
Redd MA, Scheuer SE, Saez NJ, Yoshikawa Y, Chiu HS, Gao L, Hicks M, Villanueva JE, Joshi Y, Chow CY, Cuellar-Partida G, Peart JN, See Hoe LE, Chen X, Sun Y, Suen JY, Hatch RJ, Rollo B, Xia D, Alzubaidi MAH, Maljevic S, Quaife-Ryan GA, Hudson JE, Porrello ER, White MY, Cordwell SJ, Fraser JF, Petrou S, Reichelt ME, Thomas WG, King GF, Macdonald PS, Palpant NJ. Redd MA, et al. Among authors: saez nj. Circulation. 2021 Sep 21;144(12):947-960. doi: 10.1161/CIRCULATIONAHA.121.054360. Epub 2021 Jul 15. Circulation. 2021. PMID: 34264749 Free article.
A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
Reynaud S, Ciolek J, Degueldre M, Saez NJ, Sequeira AF, Duhoo Y, Brás JLA, Meudal H, Cabo Díez M, Fernández Pedrosa V, Verdenaud M, Boeri J, Pereira Ramos O, Ducancel F, Vanden Driessche M, Fourmy R, Violette A, Upert G, Mourier G, Beck-Sickinger AG, Mörl K, Landon C, Fontes CMGA, Miñambres Herráiz R, Rodríguez de la Vega RC, Peigneur S, Tytgat J, Quinton L, De Pauw E, Vincentelli R, Servent D, Gilles N. Reynaud S, et al. Among authors: saez nj. J Med Chem. 2020 Aug 13;63(15):8250-8264. doi: 10.1021/acs.jmedchem.0c00485. Epub 2020 Jul 16. J Med Chem. 2020. PMID: 32602722
High-Throughput Production of Oxidized Animal Toxins in Escherichia coli.
Duhoo Y, Sequeira AF, Saez NJ, Turchetto J, Ramond L, Peysson F, Brás JLA, Gilles N, Darbon H, Fontes CMGA, Vincentelli R. Duhoo Y, et al. Among authors: saez nj. Methods Mol Biol. 2019;2025:165-190. doi: 10.1007/978-1-4939-9624-7_7. Methods Mol Biol. 2019. PMID: 31267452
26 results