Sadybekov AV - Search Results

1

Structure-Based Virtual Screening of Ultra-Large Library Yields Potent Antagonists for a Lipid GPCR.

Sadybekov AA, Brouillette RL, Marin E, Sadybekov AV, Luginina A, Gusach A, Mishin A, Besserer-Offroy É, Longpré JM, Borshchevskiy V, Cherezov V, Sarret P, Katritch V. Sadybekov AA, et al. Among authors: sadybekov av. Biomolecules. 2020 Dec 3;10(12):1634. doi: 10.3390/biom10121634. Biomolecules. 2020. PMID: 33287369 Free PMC article.

2

Structural basis for selectivity and diversity in angiotensin II receptors.

Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V. Zhang H, et al. Nature. 2017 Apr 20;544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5. Nature. 2017. PMID: 28379944 Free PMC article.

3

An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio.

Sadybekov A, Tian C, Arnesano C, Katritch V, Herring BE. Sadybekov A, et al. Nat Commun. 2017 Sep 19;8(1):601. doi: 10.1038/s41467-017-00472-0. Nat Commun. 2017. PMID: 28928363 Free PMC article.

4

An Intellectual Disability-Related Missense Mutation in Rac1 Prevents LTP Induction.

Tian C, Kay Y, Sadybekov A, Rao S, Katritch V, Herring BE. Tian C, et al. Front Mol Neurosci. 2018 Jul 6;11:223. doi: 10.3389/fnmol.2018.00223. eCollection 2018. Front Mol Neurosci. 2018. PMID: 30042656 Free PMC article.

5

Breaking the Enigma Code of Angiotensin II Type 2 Receptor Signaling.

Sadybekov A, Katritch V. Sadybekov A, et al. Structure. 2020 Apr 7;28(4):390-392. doi: 10.1016/j.str.2020.03.004. Structure. 2020. PMID: 32268077 Free PMC article.

6

Optical Control of Cannabinoid Receptor 2-Mediated Ca²⁺ Release Enabled by Synthesis of Photoswitchable Probes.

Sarott RC, Viray AEG, Pfaff P, Sadybekov A, Rajic G, Katritch V, Carreira EM, Frank JA. Sarott RC, et al. J Am Chem Soc. 2021 Jan 20;143(2):736-743. doi: 10.1021/jacs.0c08926. Epub 2021 Jan 5. J Am Chem Soc. 2021. PMID: 33399457

7

Structural insights on ligand recognition at the human leukotriene B4 receptor 1.

Michaelian N, Sadybekov A, Besserer-Offroy É, Han GW, Krishnamurthy H, Zamlynny BA, Fradera X, Siliphaivanh P, Presland J, Spencer KB, Soisson SM, Popov P, Sarret P, Katritch V, Cherezov V. Michaelian N, et al. Nat Commun. 2021 May 20;12(1):2971. doi: 10.1038/s41467-021-23149-1. Nat Commun. 2021. PMID: 34016973 Free PMC article.

8

Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.

Sadybekov AA, Sadybekov AV, Liu Y, Iliopoulos-Tsoutsouvas C, Huang XP, Pickett J, Houser B, Patel N, Tran NK, Tong F, Zvonok N, Jain MK, Savych O, Radchenko DS, Nikas SP, Petasis NA, Moroz YS, Roth BL, Makriyannis A, Katritch V. Sadybekov AA, et al. Among authors: sadybekov av. Nature. 2022 Jan;601(7893):452-459. doi: 10.1038/s41586-021-04220-9. Epub 2021 Dec 15. Nature. 2022. PMID: 34912117 Free PMC article.

9

Schizophrenia-associated SAP97 mutations increase glutamatergic synapse strength in the dentate gyrus and impair contextual episodic memory in rats.

Kay Y, Tsan L, Davis EA, Tian C, Décarie-Spain L, Sadybekov A, Pushkin AN, Katritch V, Kanoski SE, Herring BE. Kay Y, et al. Nat Commun. 2022 Feb 10;13(1):798. doi: 10.1038/s41467-022-28430-5. Nat Commun. 2022. PMID: 35145085 Free PMC article.

10

Eosinophils protect pressure overload- and β-adrenoreceptor agonist-induced cardiac hypertrophy.

Yang C, Li J, Deng Z, Luo S, Liu J, Fang W, Liu F, Liu T, Zhang X, Zhang Y, Meng Z, Zhang S, Luo J, Liu C, Yang D, Liu L, Sukhova GK, Sadybekov A, Katritch V, Libby P, Wang J, Guo J, Shi GP. Yang C, et al. Cardiovasc Res. 2023 Mar 17;119(1):195-212. doi: 10.1093/cvr/cvac060. Cardiovasc Res. 2023. PMID: 35394031 Free PMC article.

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