Sacchettini J - Search Results

1

The TB structural genomics consortium: providing a structural foundation for drug discovery.

Goulding CW, Apostol M, Anderson DH, Gill HS, Smith CV, Kuo MR, Yang JK, Waldo GS, Suh SW, Chauhan R, Kale A, Bachhawat N, Mande SC, Johnston JM, Lott JS, Baker EN, Arcus VL, Leys D, McLean KJ, Munro AW, Berendzen J, Sharma V, Park MS, Eisenberg D, Sacchettini J, Alber T, Rupp B, Jacobs W Jr, Terwilliger TC. Goulding CW, et al. Among authors: sacchettini j. Curr Drug Targets Infect Disord. 2002 Jun;2(2):121-41. doi: 10.2174/1568005023342551. Curr Drug Targets Infect Disord. 2002. PMID: 12462144 Review.

2

Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis.

Dessen A, Quémard A, Blanchard JS, Jacobs WR Jr, Sacchettini JC. Dessen A, et al. Among authors: sacchettini jc. Science. 1995 Mar 17;267(5204):1638-41. doi: 10.1126/science.7886450. Science. 1995. PMID: 7886450

3

Modification of the NADH of the isoniazid target (InhA) from Mycobacterium tuberculosis.

Rozwarski DA, Grant GA, Barton DH, Jacobs WR Jr, Sacchettini JC. Rozwarski DA, et al. Among authors: sacchettini jc. Science. 1998 Jan 2;279(5347):98-102. doi: 10.1126/science.279.5347.98. Science. 1998. PMID: 9417034

4

The mabA gene from the inhA operon of Mycobacterium tuberculosis encodes a 3-ketoacyl reductase that fails to confer isoniazid resistance.

Banerjee A, Sugantino M, Sacchettini JC, Jacobs WR. Banerjee A, et al. Microbiology (Reading). 1998 Oct;144 ( Pt 10):2697-2704. doi: 10.1099/00221287-144-10-2697. Microbiology (Reading). 1998. PMID: 9802011 Free article.

5

Crystal structure of quinolinic acid phosphoribosyltransferase from Mmycobacterium tuberculosis: a potential TB drug target.

Sharma V, Grubmeyer C, Sacchettini JC. Sharma V, et al. Among authors: sacchettini jc. Structure. 1998 Dec 15;6(12):1587-99. doi: 10.1016/s0969-2126(98)00156-7. Structure. 1998. PMID: 9862811 Free article.

6

Inactivation of the inhA-encoded fatty acid synthase II (FASII) enoyl-acyl carrier protein reductase induces accumulation of the FASI end products and cell lysis of Mycobacterium smegmatis.

Vilchèze C, Morbidoni HR, Weisbrod TR, Iwamoto H, Kuo M, Sacchettini JC, Jacobs WR Jr. Vilchèze C, et al. Among authors: sacchettini jc. J Bacteriol. 2000 Jul;182(14):4059-67. doi: 10.1128/JB.182.14.4059-4067.2000. J Bacteriol. 2000. PMID: 10869086 Free PMC article.

7

Crystal structures of mycolic acid cyclopropane synthases from Mycobacterium tuberculosis.

Huang CC, Smith CV, Glickman MS, Jacobs WR Jr, Sacchettini JC. Huang CC, et al. J Biol Chem. 2002 Mar 29;277(13):11559-69. doi: 10.1074/jbc.M111698200. Epub 2001 Dec 26. J Biol Chem. 2002. PMID: 11756461 Free article.

8

Biochemical and structural studies of malate synthase from Mycobacterium tuberculosis.

Smith CV, Huang CC, Miczak A, Russell DG, Sacchettini JC, Höner zu Bentrup K. Smith CV, et al. J Biol Chem. 2003 Jan 17;278(3):1735-43. doi: 10.1074/jbc.M209248200. Epub 2002 Oct 21. J Biol Chem. 2003. PMID: 12393860 Free article.

9

PHENIX: building new software for automated crystallographic structure determination.

Adams PD, Grosse-Kunstleve RW, Hung LW, Ioerger TR, McCoy AJ, Moriarty NW, Read RJ, Sacchettini JC, Sauter NK, Terwilliger TC. Adams PD, et al. Among authors: sacchettini jc. Acta Crystallogr D Biol Crystallogr. 2002 Nov;58(Pt 11):1948-54. doi: 10.1107/s0907444902016657. Epub 2002 Oct 21. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12393927

10

Crystal structure of ATP phosphoribosyltransferase from Mycobacterium tuberculosis.

Cho Y, Sharma V, Sacchettini JC. Cho Y, et al. J Biol Chem. 2003 Mar 7;278(10):8333-9. doi: 10.1074/jbc.M212124200. Epub 2003 Jan 2. J Biol Chem. 2003. PMID: 12511575 Free article.

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