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Loss of hepatic DEPTOR alters the metabolic transition to fasting.
Caron A, Mouchiroud M, Gautier N, Labbé SM, Villot R, Turcotte L, Secco B, Lamoureux G, Shum M, Gélinas Y, Marette A, Richard D, Sabatini DM, Laplante M. Caron A, et al. Among authors: sabatini dm. Mol Metab. 2017 Feb 17;6(5):447-458. doi: 10.1016/j.molmet.2017.02.005. eCollection 2017 May. Mol Metab. 2017. PMID: 28462079 Free PMC article.
PRAS40 is an insulin-regulated inhibitor of the mTORC1 protein kinase.
Sancak Y, Thoreen CC, Peterson TR, Lindquist RA, Kang SA, Spooner E, Carr SA, Sabatini DM. Sancak Y, et al. Among authors: sabatini dm. Mol Cell. 2007 Mar 23;25(6):903-15. doi: 10.1016/j.molcel.2007.03.003. Mol Cell. 2007. PMID: 17386266 Free article.
Increased mTORC1 signaling UPRegulates stress.
Reiling JH, Sabatini DM. Reiling JH, et al. Among authors: sabatini dm. Mol Cell. 2008 Mar 14;29(5):533-5. doi: 10.1016/j.molcel.2008.02.011. Mol Cell. 2008. PMID: 18342598 Free article.
mTOR signaling at a glance.
Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. J Cell Sci. 2009 Oct 15;122(Pt 20):3589-94. doi: 10.1242/jcs.051011. J Cell Sci. 2009. PMID: 19812304 Free PMC article. Review. No abstract available.
An emerging role of mTOR in lipid biosynthesis.
Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. Curr Biol. 2009 Dec 1;19(22):R1046-52. doi: 10.1016/j.cub.2009.09.058. Curr Biol. 2009. PMID: 19948145 Free PMC article. Review.
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.
Laplante M, Sabatini DM. Laplante M, et al. Among authors: sabatini dm. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3281-2. doi: 10.1073/pnas.1000323107. Epub 2010 Feb 18. Proc Natl Acad Sci U S A. 2010. PMID: 20167806 Free PMC article. No abstract available.
287 results