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Target-based drug discovery through inversion of quantitative structure-drug-property relationships and molecular simulation: CA IX-sulphonamide complexes.
Žuvela P, Liu JJ, Yi M, Pomastowski PP, Sagandykova G, Belka M, David J, Bączek T, Szafrański K, Żołnowska B, Sławiński J, Supuran CT, Wong MW, Buszewski B. Žuvela P, et al. Among authors: slawinski j. J Enzyme Inhib Med Chem. 2018 Dec;33(1):1430-1443. doi: 10.1080/14756366.2018.1511551. J Enzyme Inhib Med Chem. 2018. PMID: 30220229 Free PMC article.
Carbonic anhydrase inhibitors. Inhibition of the cytosolic human isozymes I and II, and the transmembrane, tumor-associated isozymes IX and XII with substituted aromatic sulfonamides activatable in hypoxic tumors.
Saczewski F, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Innocenti A, Scozzafava A, Supuran CT. Saczewski F, et al. Among authors: slawinski j. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4846-51. doi: 10.1016/j.bmcl.2006.06.064. Epub 2006 Jun 30. Bioorg Med Chem Lett. 2006. PMID: 16809036
Carbonic anhydrase inhibitors. Selective inhibition of human tumor-associated isozymes IX and XII and cytosolic isozymes I and II with some substituted-2-mercapto-benzenesulfonamides.
Saczewski F, Innocenti A, Brzozowski Z, Slawiński J, Pomarnacka E, Kornicka A, Scozzafava A, Supuran CT. Saczewski F, et al. Among authors: slawinski j. J Enzyme Inhib Med Chem. 2006 Oct;21(5):563-8. doi: 10.1080/14756360600648146. J Enzyme Inhib Med Chem. 2006. PMID: 17194028
Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides.
Saczewski F, Innocenti A, Sławiński J, Kornicka A, Brzozowski Z, Pomarnacka E, Scozzafava A, Temperini C, Supuran CT. Saczewski F, et al. Among authors: slawinski j. Bioorg Med Chem. 2008 Apr 1;16(7):3933-40. doi: 10.1016/j.bmc.2008.01.034. Epub 2008 Jan 26. Bioorg Med Chem. 2008. PMID: 18242998
Carbonic anhydrase inhibitors. Regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
Brzozowski Z, Sławiński J, Innocenti A, Supuran CT. Brzozowski Z, et al. Among authors: slawinski j. Eur J Med Chem. 2010 Sep;45(9):3656-61. doi: 10.1016/j.ejmech.2010.05.011. Epub 2010 May 12. Eur J Med Chem. 2010. PMID: 20554082
Carbonic anhydrase inhibitors. Synthesis, molecular structures, and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with novel 3-pyridinesulfonamide derivatives.
Brzozowski Z, Sławiński J, Gdaniec M, Innocenti A, Supuran CT. Brzozowski Z, et al. Among authors: slawinski j. Eur J Med Chem. 2011 Sep;46(9):4403-10. doi: 10.1016/j.ejmech.2011.07.011. Epub 2011 Jul 8. Eur J Med Chem. 2011. PMID: 21820216
Carbonic anhydrase inhibitors. Regioselective synthesis of novel series 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer-associated isozymes IX and XII.
Brzozowski Z, Sławiński J, Vullo D, Supuran CT. Brzozowski Z, et al. Among authors: slawinski j. Eur J Med Chem. 2012 Oct;56:282-91. doi: 10.1016/j.ejmech.2012.08.006. Epub 2012 Aug 11. Eur J Med Chem. 2012. PMID: 22910138
150 results