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94 results

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Page 1
RNA helicase DHX15 exemplifies a unique dependency in acute leukemia.
Guo H, Xu J, Xing P, Li Q, Wang D, Tang C, Palhais B, Roels J, Liu J, Pan S, Huang J, Liu Z, Zhu P, Taghon T, Qing G, Van Vlierberghe P, Liu H. Guo H, et al. Among authors: roels j. Haematologica. 2023 Aug 1;108(8):2029-2043. doi: 10.3324/haematol.2022.282066. Haematologica. 2023. PMID: 36861414 Free PMC article.
Restoration of Endogenous Retrovirus Infectivity Impacts Mouse Cancer Models.
Ottina E, Levy P, Eksmond U, Merkenschlager J, Young GR, Roels J, Stoye JP, Tüting T, Calado DP, Kassiotis G. Ottina E, et al. Among authors: roels j. Cancer Immunol Res. 2018 Nov;6(11):1292-1300. doi: 10.1158/2326-6066.CIR-18-0038. Epub 2018 Aug 24. Cancer Immunol Res. 2018. PMID: 30143537 Free PMC article.
Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma.
De Smedt R, Peirs S, Morscio J, Matthijssens F, Roels J, Reunes L, Lintermans B, Goossens S, Lammens T, Van Roy N, Touzart A, Jenni S, Tsai YC, Lovisa F, Mussolin L, Serafin V, Van Nieuwerburgh F, Deforce D, Uyttebroeck A, Tousseyn T, Burkhardt B, Klapper W, De Moerloose B, Benoit Y, Macintyre E, Bourquin JP, Basso G, Accordi B, Bornhauser B, Meijerink J, Vandenberghe P, Van Vlierberghe P. De Smedt R, et al. Among authors: roels j. Haematologica. 2019 Jan;104(1):e17-e20. doi: 10.3324/haematol.2018.199257. Epub 2018 Aug 3. Haematologica. 2019. PMID: 30076176 Free PMC article. No abstract available.
Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development.
Dolens AC, Durinck K, Lavaert M, Van der Meulen J, Velghe I, De Medts J, Weening K, Roels J, De Mulder K, Volders PJ, De Preter K, Kerre T, Vandekerckhove B, Leclercq G, Vandesompele J, Mestdagh P, Van Vlierberghe P, Speleman F, Taghon T. Dolens AC, et al. Among authors: roels j. EMBO Rep. 2020 May 6;21(5):e49006. doi: 10.15252/embr.201949006. Epub 2020 Apr 7. EMBO Rep. 2020. PMID: 32255245 Free PMC article.
Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes.
Lavaert M, Liang KL, Vandamme N, Park JE, Roels J, Kowalczyk MS, Li B, Ashenberg O, Tabaka M, Dionne D, Tickle TL, Slyper M, Rozenblatt-Rosen O, Vandekerckhove B, Leclercq G, Regev A, Van Vlierberghe P, Guilliams M, Teichmann SA, Saeys Y, Taghon T. Lavaert M, et al. Among authors: roels j. Immunity. 2020 Jun 16;52(6):1088-1104.e6. doi: 10.1016/j.immuni.2020.03.019. Epub 2020 Apr 17. Immunity. 2020. PMID: 32304633 Free article.
Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma.
De Smedt R, Morscio J, Reunes L, Roels J, Bardelli V, Lintermans B, Van Loocke W, Almeida A, Cheung LC, Kotecha RS, Mansour MR, Uyttebroeck A, Vandenberghe P, La Starza R, Mecucci C, Lammens T, Van Roy N, De Moerloose B, Barata JT, Taghon T, Goossens S, Van Vlierberghe P. De Smedt R, et al. Among authors: roels j. Blood. 2020 May 7;135(19):1685-1695. doi: 10.1182/blood.2019003880. Blood. 2020. PMID: 32315407 Free article.
The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation.
Taveirne S, Wahlen S, Van Loocke W, Kiekens L, Persyn E, Van Ammel E, De Mulder K, Roels J, Tilleman L, Aumercier M, Matthys P, Van Nieuwerburgh F, Kerre TCC, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Taveirne S, et al. Among authors: roels j. Blood. 2020 Jul 16;136(3):288-298. doi: 10.1182/blood.2020005204. Blood. 2020. PMID: 32350509 Free article.
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, Declerck K, Lammens T, De Moerloose B, Deforce D, Van Nieuwerburgh F, Cheung LC, Kotecha RS, Mansour MR, Ghesquière B, Van Camp G, Berghe WV, Kowalczyk JR, Szczepański T, Davé UP, Kulozik AE, Goossens S, Curtis DJ, Taghon T, Dawidowska M, Degerman S, Van Vlierberghe P. Roels J, et al. Blood Cancer Discov. 2020 Nov;1(3):274-289. doi: 10.1158/2643-3230.BCD-20-0059. Epub 2020 Sep 23. Blood Cancer Discov. 2020. PMID: 33179015 Free PMC article.
94 results