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Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites.
Jarrad AM, Karoli T, Debnath A, Tay CY, Huang JX, Kaeslin G, Elliott AG, Miyamoto Y, Ramu S, Kavanagh AM, Zuegg J, Eckmann L, Blaskovich MA, Cooper MA. Jarrad AM, et al. Among authors: ramu s. Eur J Med Chem. 2015 Aug 28;101:96-102. doi: 10.1016/j.ejmech.2015.06.019. Epub 2015 Jun 18. Eur J Med Chem. 2015. PMID: 26117821 Free PMC article.
Structure aided design of chimeric antibiotics.
Karoli T, Mamidyala SK, Zuegg J, Fry SR, Tee EH, Bradford TA, Madala PK, Huang JX, Ramu S, Butler MS, Cooper MA. Karoli T, et al. Among authors: ramu s. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2428-33. doi: 10.1016/j.bmcl.2012.02.019. Epub 2012 Feb 22. Bioorg Med Chem Lett. 2012. PMID: 22406152
A new antibiotic with potent activity targets MscL.
Iscla I, Wray R, Blount P, Larkins-Ford J, Conery AL, Ausubel FM, Ramu S, Kavanagh A, Huang JX, Blaskovich MA, Cooper MA, Obregon-Henao A, Orme I, Tjandra ES, Stroeher UH, Brown MH, Macardle C, van Holst N, Ling Tong C, Slattery AD, Gibson CT, Raston CL, Boulos RA. Iscla I, et al. Among authors: ramu s. J Antibiot (Tokyo). 2015 Jul;68(7):453-62. doi: 10.1038/ja.2015.4. Epub 2015 Feb 4. J Antibiot (Tokyo). 2015. PMID: 25649856 Free PMC article.
Mucin Binding Reduces Colistin Antimicrobial Activity.
Huang JX, Blaskovich MA, Pelingon R, Ramu S, Kavanagh A, Elliott AG, Butler MS, Montgomery AB, Cooper MA. Huang JX, et al. Among authors: ramu s. Antimicrob Agents Chemother. 2015 Oct;59(10):5925-31. doi: 10.1128/AAC.00808-15. Epub 2015 Jul 13. Antimicrob Agents Chemother. 2015. PMID: 26169405 Free PMC article.
106 results