R56 AI106005/AI/NIAID NIH HHS/United States[Grants and Funding] - Search Results

Year	Number of Results
2014	3
2015	7
2016	5
2017	1
2018	1
2019	3
2021	1
2024	0

1

Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.

Chen F, Tzarum N, Lin X, Giang E, Velázquez-Moctezuma R, Augestad EH, Nagy K, He L, Hernandez M, Fouch ME, Grinyó A, Chavez D, Doranz BJ, Prentoe J, Stanfield RL, Lanford R, Bukh J, Wilson IA, Zhu J, Law M. Chen F, et al. Immunity. 2021 Apr 13;54(4):781-796.e4. doi: 10.1016/j.immuni.2021.02.013. Epub 2021 Mar 5. Immunity. 2021. PMID: 33675683 Free PMC article.

2

Hypervariable region 1 and N-linked glycans of hepatitis C regulate virion neutralization by modulating envelope conformations.

Prentoe J, Velázquez-Moctezuma R, Augestad EH, Galli A, Wang R, Law M, Alter H, Bukh J. Prentoe J, et al. Proc Natl Acad Sci U S A. 2019 May 14;116(20):10039-10047. doi: 10.1073/pnas.1822002116. Epub 2019 Apr 30. Proc Natl Acad Sci U S A. 2019. PMID: 31040211 Free PMC article.

3

V_H1-69 antiviral broadly neutralizing antibodies: genetics, structures, and relevance to rational vaccine design.

Chen F, Tzarum N, Wilson IA, Law M. Chen F, et al. Curr Opin Virol. 2019 Feb;34:149-159. doi: 10.1016/j.coviro.2019.02.004. Epub 2019 Mar 16. Curr Opin Virol. 2019. PMID: 30884330 Free PMC article. Review.

4

Hepatitis C Virus Escape Studies of Human Antibody AR3A Reveal a High Barrier to Resistance and Novel Insights on Viral Antibody Evasion Mechanisms.

Velázquez-Moctezuma R, Galli A, Law M, Bukh J, Prentoe J. Velázquez-Moctezuma R, et al. J Virol. 2019 Feb 5;93(4):e01909-18. doi: 10.1128/JVI.01909-18. Print 2019 Feb 15. J Virol. 2019. PMID: 30487284 Free PMC article.

5

Immunogenetic and structural analysis of a class of HCV broadly neutralizing antibodies and their precursors.

Aleman F, Tzarum N, Kong L, Nagy K, Zhu J, Wilson IA, Law M. Aleman F, et al. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7569-7574. doi: 10.1073/pnas.1802378115. Epub 2018 Jun 28. Proc Natl Acad Sci U S A. 2018. PMID: 29954862 Free PMC article.

6

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis.

Gopal R, Jackson K, Tzarum N, Kong L, Ettenger A, Guest J, Pfaff JM, Barnes T, Honda A, Giang E, Davidson E, Wilson IA, Doranz BJ, Law M. Gopal R, et al. PLoS Pathog. 2017 Dec 18;13(12):e1006735. doi: 10.1371/journal.ppat.1006735. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29253863 Free PMC article.

7

Structural flexibility at a major conserved antibody target on hepatitis C virus E2 antigen.

Kong L, Lee DE, Kadam RU, Liu T, Giang E, Nieusma T, Garces F, Tzarum N, Woods VL Jr, Ward AB, Li S, Wilson IA, Law M. Kong L, et al. Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12768-12773. doi: 10.1073/pnas.1609780113. Epub 2016 Oct 24. Proc Natl Acad Sci U S A. 2016. PMID: 27791120 Free PMC article.

8

Hypervariable region 1 shielding of hepatitis C virus is a main contributor to genotypic differences in neutralization sensitivity.

Prentoe J, Velázquez-Moctezuma R, Foung SK, Law M, Bukh J. Prentoe J, et al. Hepatology. 2016 Dec;64(6):1881-1892. doi: 10.1002/hep.28705. Epub 2016 Aug 9. Hepatology. 2016. PMID: 27351277 Free PMC article.

9

Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens.

von Schaewen M, Hrebikova G, Ploss A. von Schaewen M, et al. Methods Mol Biol. 2016;1438:79-101. doi: 10.1007/978-1-4939-3661-8_5. Methods Mol Biol. 2016. PMID: 27150085

10

In vivo models of hepatitis B and C virus infection.

Winer BY, Ding Q, Gaska JM, Ploss A. Winer BY, et al. FEBS Lett. 2016 Jul;590(13):1987-99. doi: 10.1002/1873-3468.12157. Epub 2016 Apr 8. FEBS Lett. 2016. PMID: 27009462 Free PMC article. Review.

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