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Copper Modulates the Catalytic Activity of Protein Kinase CK2.
Chojnowski JE, Li R, Tsang T, Alfaran FH, Dick A, Cocklin S, Brady DC, Strochlic TI. Chojnowski JE, et al. Front Mol Biosci. 2022 Jun 9;9:878652. doi: 10.3389/fmolb.2022.878652. eCollection 2022. Front Mol Biosci. 2022. PMID: 35755824 Free PMC article.
Connecting copper and cancer: from transition metal signalling to metalloplasia.
Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. Ge EJ, et al. Nat Rev Cancer. 2022 Feb;22(2):102-113. doi: 10.1038/s41568-021-00417-2. Epub 2021 Nov 11. Nat Rev Cancer. 2022. PMID: 34764459 Free PMC article. Review.
The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation.
Grasso M, Bond GJ, Kim YJ, Boyd S, Matson Dzebo M, Valenzuela S, Tsang T, Schibrowsky NA, Alwan KB, Blackburn NJ, Burslem GM, Wittung-Stafshede P, Winkler DD, Marmorstein R, Brady DC. Grasso M, et al. J Biol Chem. 2021 Dec;297(6):101314. doi: 10.1016/j.jbc.2021.101314. Epub 2021 Oct 27. J Biol Chem. 2021. PMID: 34715128 Free PMC article.
12 results