R01 GM120502/GM/NIGMS NIH HHS/United States[Grants and Funding] - Search Results

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Subject: R01 GM120502/GM/NIGMS NIH HHS/United States[Grant - PubMed

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Year	Number of Results
2018	2
2020	4
2021	1
2023	1
2024	1

8 results

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MLKL polymerization-induced lysosomal membrane permeabilization promotes necroptosis.

Liu S, Perez P, Sun X, Chen K, Fatirkhorani R, Mammadova J, Wang Z. Liu S, et al. Cell Death Differ. 2024 Jan;31(1):40-52. doi: 10.1038/s41418-023-01237-7. Epub 2023 Nov 23. Cell Death Differ. 2024. PMID: 37996483 Free PMC article.

RIPK1 dephosphorylation and kinase activation by PPP1R3G/PP1γ promote apoptosis and necroptosis.

Du J, Xiang Y, Liu H, Liu S, Kumar A, Xing C, Wang Z. Du J, et al. Nat Commun. 2021 Dec 3;12(1):7067. doi: 10.1038/s41467-021-27367-5. Nat Commun. 2021. PMID: 34862394 Free PMC article.

HSP70 promotes MLKL polymerization and necroptosis.

Johnston AN, Wang Z. Johnston AN, et al. Mol Cell Oncol. 2020 Jul 14;7(5):1791561. doi: 10.1080/23723556.2020.1791561. eCollection 2020. Mol Cell Oncol. 2020. PMID: 32944645 Free PMC article.

Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics.

Yu B, Ma J, Li J, Wang D, Wang Z, Wang S. Yu B, et al. Nat Commun. 2020 May 21;11(1):2549. doi: 10.1038/s41467-020-16312-7. Nat Commun. 2020. PMID: 32439975 Free PMC article.

Necroptosis-blocking compound NBC1 targets heat shock protein 70 to inhibit MLKL polymerization and necroptosis.

Johnston AN, Ma Y, Liu H, Liu S, Hanna-Addams S, Chen S, Chen C, Wang Z. Johnston AN, et al. Proc Natl Acad Sci U S A. 2020 Mar 24;117(12):6521-6530. doi: 10.1073/pnas.1916503117. Epub 2020 Mar 10. Proc Natl Acad Sci U S A. 2020. PMID: 32156734 Free PMC article.

CK1α, CK1δ, and CK1ε are necrosome components which phosphorylate serine 227 of human RIPK3 to activate necroptosis.

Hanna-Addams S, Liu S, Liu H, Chen S, Wang Z. Hanna-Addams S, et al. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):1962-1970. doi: 10.1073/pnas.1917112117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932442 Free PMC article.

Necroptosis: MLKL Polymerization.

Johnston A, Wang Z. Johnston A, et al. J Nat Sci. 2018 Jul;4(7):e513. J Nat Sci. 2018. PMID: 30294675 Free PMC article.

Use of Two Dimensional Semi-denaturing Detergent Agarose Gel Electrophoresis to Confirm Size Heterogeneity of Amyloid or Amyloid-like Fibers.

Hanna-Addams S, Wang Z. Hanna-Addams S, et al. J Vis Exp. 2018 Apr 26;(134):57498. doi: 10.3791/57498. J Vis Exp. 2018. PMID: 29757289 Free PMC article.

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