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Multi-antigen spherical nucleic acid cancer vaccines.
Teplensky MH, Evangelopoulos M, Dittmar JW, Forsyth CM, Sinegra AJ, Wang S, Mirkin CA. Teplensky MH, et al. Nat Biomed Eng. 2023 Jul;7(7):911-927. doi: 10.1038/s41551-022-01000-2. Epub 2023 Jan 30. Nat Biomed Eng. 2023. PMID: 36717738 Free PMC article.
Spherical nucleic acids as an infectious disease vaccine platform.
Teplensky MH, Distler ME, Kusmierz CD, Evangelopoulos M, Gula H, Elli D, Tomatsidou A, Nicolaescu V, Gelarden I, Yeldandi A, Batlle D, Missiakas D, Mirkin CA. Teplensky MH, et al. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2119093119. doi: 10.1073/pnas.2119093119. Epub 2022 Mar 21. Proc Natl Acad Sci U S A. 2022. PMID: 35312341 Free PMC article.
Hairpin-like siRNA-Based Spherical Nucleic Acids.
Vasher MK, Yamankurt G, Mirkin CA. Vasher MK, et al. J Am Chem Soc. 2022 Feb 23;144(7):3174-3181. doi: 10.1021/jacs.1c12750. Epub 2022 Feb 10. J Am Chem Soc. 2022. PMID: 35143189 Free PMC article.
A first-in-human phase 0 clinical study of RNA interference-based spherical nucleic acids in patients with recurrent glioblastoma.
Kumthekar P, Ko CH, Paunesku T, Dixit K, Sonabend AM, Bloch O, Tate M, Schwartz M, Zuckerman L, Lezon R, Lukas RV, Jovanovic B, McCortney K, Colman H, Chen S, Lai B, Antipova O, Deng J, Li L, Tommasini-Ghelfi S, Hurley LA, Unruh D, Sharma NV, Kandpal M, Kouri FM, Davuluri RV, Brat DJ, Muzzio M, Glass M, Vijayakumar V, Heidel J, Giles FJ, Adams AK, James CD, Woloschak GE, Horbinski C, Stegh AH. Kumthekar P, et al. Sci Transl Med. 2021 Mar 10;13(584):eabb3945. doi: 10.1126/scitranslmed.abb3945. Sci Transl Med. 2021. PMID: 33692132 Free PMC article. Clinical Trial.
20 results