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The Consequences of Overlapping G-Quadruplexes and i-Motifs in the Platelet-Derived Growth Factor Receptor β Core Promoter Nuclease Hypersensitive Element Can Explain the Unexpected Effects of Mutations and Provide Opportunities for Selective Targeting of Both Structures by Small Molecules To Downregulate Gene Expression.
Brown RV, Wang T, Chappeta VR, Wu G, Onel B, Chawla R, Quijada H, Camp SM, Chiang ET, Lassiter QR, Lee C, Phanse S, Turnidge MA, Zhao P, Garcia JGN, Gokhale V, Yang D, Hurley LH. Brown RV, et al. J Am Chem Soc. 2017 Jun 7;139(22):7456-7475. doi: 10.1021/jacs.6b10028. Epub 2017 May 19. J Am Chem Soc. 2017. PMID: 28471683 Free PMC article.
Structurally Diverse Alkaloids from the Seeds of Peganum harmala.
Wang KB, Li DH, Bao Y, Cao F, Wang WJ, Lin C, Bin W, Bai J, Pei YH, Jing YK, Yang D, Li ZL, Hua HM. Wang KB, et al. J Nat Prod. 2017 Feb 24;80(2):551-559. doi: 10.1021/acs.jnatprod.6b01146. Epub 2017 Jan 27. J Nat Prod. 2017. PMID: 28128938 Free PMC article.
14 results