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Year Number of Results
2016 2
2017 6
2018 6
2019 4
2021 2
2022 2
2023 1
2024 0

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Page 1
A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation.
Ernst O, Sun J, Lin B, Banoth B, Dorrington MG, Liang J, Schwarz B, Stromberg KA, Katz S, Vayttaden SJ, Bradfield CJ, Slepushkina N, Rice CM, Buehler E, Khillan JS, McVicar DW, Bosio CM, Bryant CE, Sutterwala FS, Martin SE, Lal-Nag M, Fraser IDC. Ernst O, et al. Sci Signal. 2021 Aug 3;14(694):eabe0387. doi: 10.1126/scisignal.abe0387. Sci Signal. 2021. PMID: 34344832 Free PMC article.
Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Dagvadorj J, et al. Proc Natl Acad Sci U S A. 2021 Jan 5;118(1):e2015632118. doi: 10.1073/pnas.2015632118. Proc Natl Acad Sci U S A. 2021. PMID: 33361152 Free PMC article.
Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A.
Borbón TY, Scorza BM, Clay GM, Lima Nobre de Queiroz F, Sariol AJ, Bowen JL, Chen Y, Zhanbolat B, Parlet CP, Valadares DG, Cassel SL, Nauseef WM, Horswill AR, Sutterwala FS, Wilson ME. Borbón TY, et al. PLoS Negl Trop Dis. 2019 May 20;13(5):e0007247. doi: 10.1371/journal.pntd.0007247. eCollection 2019 May. PLoS Negl Trop Dis. 2019. PMID: 31107882 Free PMC article.
Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.
Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W. Kolb R, et al. Oncogene. 2019 Mar;38(13):2351-2363. doi: 10.1038/s41388-018-0592-6. Epub 2018 Dec 5. Oncogene. 2019. PMID: 30518876 Free PMC article.
NLRP12: The Monarch of the Gut.
Sadeghi H, Devkota S, Sutterwala FS. Sadeghi H, et al. Cell Host Microbe. 2018 Sep 12;24(3):326-328. doi: 10.1016/j.chom.2018.08.010. Cell Host Microbe. 2018. PMID: 30212643 Free article.
21 results