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Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles.
Samadi A, Marco-Contelles J, Soriano E, Alvarez-Pérez M, Chioua M, Romero A, González-Lafuente L, Gandía L, Roda JM, López MG, Villarroya M, García AG, Ríos Cde L. Samadi A, et al. Bioorg Med Chem. 2010 Aug 15;18(16):5861-72. doi: 10.1016/j.bmc.2010.06.095. Epub 2010 Jul 3. Bioorg Med Chem. 2010. PMID: 20656495
Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline (LatAm-FINGERS): Study design and harmonization.
Crivelli L, Calandri IL, Suemoto CK, Salinas RM, Velilla LM, Yassuda MS, Caramelli P, Lopera F, Nitrini R, Sevlever GE, Sosa AL, Acosta D, Baietti AMC, Cusicanqui MI, Custodio N, De Simone SD, Derio CD, Duque-Peñailillo L, Duran JC, Jiménez-Velázquez IZ, Leon-Salas JM, Bergamo Y, Clarens MF, Damian A, Demey I, Helou MB, Márquez C, Martin ME, Martin MDGM, Querze D, Surace EI, Acosta-Egea S, Aguirre-Salvador E, de Souza LC, Cançado GHDCP, Brucki SMD, Friedlaender CV, Gomes KB, Gutierrez M, Ríos CL, Galindo JGM, Montesinos R, Nuñez-Herrera A, Ospina-Henao S, Rodríguez G, Masson VR, Sánchez M, Schenk CE, Soto L, Barbosa MT, Tosatti JAG, Vicuña Y, Espeland M, Hakansson K, Kivipelto M, Baker L, Snyder H, Carrillo M, Allegri RF. Crivelli L, et al. Among authors: rios cl. Alzheimers Dement. 2023 Sep;19(9):4046-4060. doi: 10.1002/alz.13101. Epub 2023 May 19. Alzheimers Dement. 2023. PMID: 37204054 Clinical Trial.
Author Correction: Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S; NHLBI Trans–Omics for Precision Medicine (TOPMed) Consortium; Rodríguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: rios cl. Nat Commun. 2022 Oct 3;13(1):5806. doi: 10.1038/s41467-022-33097-z. Nat Commun. 2022. PMID: 36192399 Free PMC article. No abstract available.
Nasal airway transcriptome-wide association study of asthma reveals genetically driven mucus pathobiology.
Sajuthi SP, Everman JL, Jackson ND, Saef B, Rios CL, Moore CM, Mak ACY, Eng C, Fairbanks-Mahnke A, Salazar S, Elhawary J, Huntsman S, Medina V, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Zaitlen NA, Oh S; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium; Rodríguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: rios cl. Nat Commun. 2022 Mar 28;13(1):1632. doi: 10.1038/s41467-022-28973-7. Nat Commun. 2022. PMID: 35347136 Free PMC article.
Type 2 and interferon inflammation regulate SARS-CoV-2 entry factor expression in the airway epithelium.
Sajuthi SP, DeFord P, Li Y, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak ACY, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: rios cl. Nat Commun. 2020 Oct 12;11(1):5139. doi: 10.1038/s41467-020-18781-2. Nat Commun. 2020. PMID: 33046696 Free PMC article.
Single-Cell and Population Transcriptomics Reveal Pan-epithelial Remodeling in Type 2-High Asthma.
Jackson ND, Everman JL, Chioccioli M, Feriani L, Goldfarbmuren KC, Sajuthi SP, Rios CL, Powell R, Armstrong M, Gomez J, Michel C, Eng C, Oh SS, Rodriguez-Santana J, Cicuta P, Reisdorph N, Burchard EG, Seibold MA. Jackson ND, et al. Among authors: rios cl. Cell Rep. 2020 Jul 7;32(1):107872. doi: 10.1016/j.celrep.2020.107872. Cell Rep. 2020. PMID: 32640237 Free PMC article.
Type 2 and interferon inflammation strongly regulate SARS-CoV-2 related gene expression in the airway epithelium.
Sajuthi SP, DeFord P, Jackson ND, Montgomery MT, Everman JL, Rios CL, Pruesse E, Nolin JD, Plender EG, Wechsler ME, Mak AC, Eng C, Salazar S, Medina V, Wohlford EM, Huntsman S, Nickerson DA, Germer S, Zody MC, Abecasis G, Kang HM, Rice KM, Kumar R, Oh S, Rodriguez-Santana J, Burchard EG, Seibold MA. Sajuthi SP, et al. Among authors: rios cl. bioRxiv [Preprint]. 2020 Apr 10:2020.04.09.034454. doi: 10.1101/2020.04.09.034454. bioRxiv. 2020. PMID: 32511326 Free PMC article. Updated. Preprint.
17 results