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Synthesis and Characterization of 4,11-Diaminoanthra[2,3-b]furan-5,10-diones: Tumor Cell Apoptosis through tNOX-Modulated NAD(+)/NADH Ratio and SIRT1.
Tikhomirov AS, Shchekotikhin AE, Lee YH, Chen YA, Yeh CA, Tatarskiy VV Jr, Dezhenkova LG, Glazunova VA, Balzarini J, Shtil AA, Preobrazhenskaya MN, Chueh PJ. Tikhomirov AS, et al. Among authors: preobrazhenskaya mn. J Med Chem. 2015 Dec 24;58(24):9522-34. doi: 10.1021/acs.jmedchem.5b00859. Epub 2015 Dec 15. J Med Chem. 2015. PMID: 26633734
Synthesis and cytotoxic properties of 4,11-bis[(aminoethyl)amino]anthra[2,3-b]thiophene-5,10-diones, novel analogues of antitumor anthracene-9,10-diones.
Shchekotikhin AE, Glazunova VA, Dezhenkova LG, Luzikov YN, Sinkevich YB, Kovalenko LV, Buyanov VN, Balzarini J, Huang FC, Lin JJ, Huang HS, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: preobrazhenskaya mn. Bioorg Med Chem. 2009 Mar 1;17(5):1861-9. doi: 10.1016/j.bmc.2009.01.047. Epub 2009 Jan 27. Bioorg Med Chem. 2009. PMID: 19208482
Reaction of the antitumor antibiotic olivomycin I with aryl diazonium salts. Synthesis, cytotoxic and antiretroviral potency of 5-aryldiazenyl-6-O-deglycosyl derivatives of olivomycin I.
Tevyashova AN, Olsufyeva EN, Turchin KF, Balzarini J, Bykov EE, Dezhenkova LG, Shtil AA, Preobrazhenskaya MN. Tevyashova AN, et al. Among authors: preobrazhenskaya mn. Bioorg Med Chem. 2009 Jul 15;17(14):4961-7. doi: 10.1016/j.bmc.2009.05.076. Epub 2009 Jun 6. Bioorg Med Chem. 2009. PMID: 19535252
The first series of 4,11-bis[(2-aminoethyl)amino]anthra[2,3-b]furan-5,10-diones: Synthesis and anti-proliferative characteristics.
Shchekotikhin AE, Glazunova VA, Dezhenkova LG, Shevtsova EK, Traven' VF, Balzarini J, Huang HS, Shtil AA, Preobrazhenskaya MN. Shchekotikhin AE, et al. Among authors: preobrazhenskaya mn. Eur J Med Chem. 2011 Jan;46(1):423-8. doi: 10.1016/j.ejmech.2010.11.017. Epub 2010 Nov 19. Eur J Med Chem. 2011. PMID: 21144624 Free article.
Modification of olivomycin A at the side chain of the aglycon yields the derivative with perspective antitumor characteristics.
Tevyashova AN, Shtil AA, Olsufyeva EN, Luzikov YN, Reznikova MI, Dezhenkova LG, Isakova EB, Bukhman VM, Durandin NA, Vinogradov AM, Kuzmin VA, Preobrazhenskaya MN. Tevyashova AN, et al. Among authors: preobrazhenskaya mn. Bioorg Med Chem. 2011 Dec 15;19(24):7387-93. doi: 10.1016/j.bmc.2011.10.055. Epub 2011 Oct 25. Bioorg Med Chem. 2011. PMID: 22088308
97 results