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The acyl-CoA synthetase TgACS1 allows neutral lipid metabolism and extracellular motility in Toxoplasma gondii through relocation via its peroxisomal targeting sequence (PTS) under low nutrient conditions.
Charital S, Shunmugam S, Dass S, Alazzi AM, Arnold C-S, Katris NJ, Duley S, Quansah NA, Pierrel F, Govin J, Yamaryo-Botté Y, Botté CY. Charital S, et al. Among authors: pierrel f. mBio. 2024 Apr 10;15(4):e0042724. doi: 10.1128/mbio.00427-24. Epub 2024 Mar 19. mBio. 2024. PMID: 38501871 Free PMC article.
Manganese-driven CoQ deficiency.
Diessl J, Berndtsson J, Broeskamp F, Habernig L, Kohler V, Vazquez-Calvo C, Nandy A, Peselj C, Drobysheva S, Pelosi L, Vögtle FN, Pierrel F, Ott M, Büttner S. Diessl J, et al. Among authors: pierrel f. Nat Commun. 2022 Oct 13;13(1):6061. doi: 10.1038/s41467-022-33641-x. Nat Commun. 2022. PMID: 36229432 Free PMC article.
Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2.
Schulz V, Basu S, Freibert SA, Webert H, Boss L, Mühlenhoff U, Pierrel F, Essen LO, Warui DM, Booker SJ, Stehling O, Lill R. Schulz V, et al. Among authors: pierrel f. Nat Chem Biol. 2023 Feb;19(2):206-217. doi: 10.1038/s41589-022-01159-4. Epub 2022 Oct 24. Nat Chem Biol. 2023. PMID: 36280795 Free PMC article.
The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.
Loiseau L, Fyfe C, Aussel L, Hajj Chehade M, Hernández SB, Faivre B, Hamdane D, Mellot-Draznieks C, Rascalou B, Pelosi L, Velours C, Cornu D, Lombard M, Casadesús J, Pierrel F, Fontecave M, Barras F. Loiseau L, et al. Among authors: pierrel f. J Biol Chem. 2017 Jul 14;292(28):11937-11950. doi: 10.1074/jbc.M117.789164. Epub 2017 May 30. J Biol Chem. 2017. PMID: 28559279 Free PMC article.
58 results