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2016 1
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Page 1
2-Oxabicyclo[2.1.1]hexanes: Synthesis, Properties, and Validation as Bioisosteres of ortho- and meta-Benzenes.
Levterov VV, Panasiuk Y, Shablykin O, Stashkevych O, Sahun K, Rassokhin A, Sadkova I, Lesyk D, Anisiforova A, Holota Y, Borysko P, Bodenchuk I, Voloshchuk NM, Mykhailiuk PK. Levterov VV, et al. Among authors: borysko p. Angew Chem Int Ed Engl. 2024 May 6;63(19):e202319831. doi: 10.1002/anie.202319831. Epub 2024 Apr 3. Angew Chem Int Ed Engl. 2024. PMID: 38465464
Spiro[3.3]heptane as a Saturated Benzene Bioisostere.
Prysiazhniuk K, Datsenko OP, Polishchuk O, Shulha S, Shablykin O, Nikandrova Y, Horbatok K, Bodenchuk I, Borysko P, Shepilov D, Pishel I, Kubyshkin V, Mykhailiuk PK. Prysiazhniuk K, et al. Among authors: borysko p. Angew Chem Int Ed Engl. 2024 Feb 26;63(9):e202316557. doi: 10.1002/anie.202316557. Epub 2024 Jan 22. Angew Chem Int Ed Engl. 2024. PMID: 38251921
Synthesis of methotrexate-betulonic acid hybrids and evaluation of their effect on artificial and Caco-2 cell membranes.
Semenenko OM, Lipson VV, Sadchenko AO, Vashchenko OV, Kasian NA, Sviechnikova LV, Lisetski LM, Babak ML, Vakula VM, Borysov OV, Holota YV, Zozulya SO, Borysko PO, Mazepa OV. Semenenko OM, et al. Among authors: borysko po. Steroids. 2024 Jan;201:109332. doi: 10.1016/j.steroids.2023.109332. Epub 2023 Nov 7. Steroids. 2024. PMID: 37939980
2-Oxabicyclo[2.2.2]octane as a new bioisostere of the phenyl ring.
Levterov VV, Panasiuk Y, Sahun K, Stashkevych O, Badlo V, Shablykin O, Sadkova I, Bortnichuk L, Klymenko-Ulianov O, Holota Y, Lachmann L, Borysko P, Horbatok K, Bodenchuk I, Bas Y, Dudenko D, Mykhailiuk PK. Levterov VV, et al. Among authors: borysko p. Nat Commun. 2023 Oct 2;14(1):5608. doi: 10.1038/s41467-023-41298-3. Nat Commun. 2023. PMID: 37783681 Free PMC article.
In Vitro Evaluation of In Silico Screening Approaches in Search for Selective ACE2 Binding Chemical Probes.
Rayevsky AV, Poturai AS, Kravets IO, Pashenko AE, Borisova TA, Tolstanova GM, Volochnyuk DM, Borysko PO, Vadzyuk OB, Alieksieieva DO, Zabolotna Y, Klimchuk O, Horvath D, Marcou G, Ryabukhin SV, Varnek A. Rayevsky AV, et al. Among authors: borysko po. Molecules. 2022 Aug 24;27(17):5400. doi: 10.3390/molecules27175400. Molecules. 2022. PMID: 36080168 Free PMC article.
Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces.
Müller J, Klein R, Tarkhanova O, Gryniukova A, Borysko P, Merkl S, Ruf M, Neumann A, Gastreich M, Moroz YS, Klebe G, Glinca S. Müller J, et al. Among authors: borysko p. J Med Chem. 2022 Dec 8;65(23):15663-15678. doi: 10.1021/acs.jmedchem.2c00813. Epub 2022 Sep 7. J Med Chem. 2022. PMID: 36069712
28 results