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Recombinant strains for the enhanced production of bioengineered rapalogs.
Kendrew SG, Petkovic H, Gaisser S, Ready SJ, Gregory MA, Coates NJ, Nur-E-Alam M, Warneck T, Suthar D, Foster TA, McDonald L, Schlingman G, Koehn FE, Skotnicki JS, Carter GT, Moss SJ, Zhang MQ, Martin CJ, Sheridan RM, Wilkinson B. Kendrew SG, et al. Among authors: petkovic h. Metab Eng. 2013 Jan;15:167-73. doi: 10.1016/j.ymben.2012.11.001. Epub 2012 Nov 17. Metab Eng. 2013. PMID: 23164580
Rapamycin biosynthesis: Elucidation of gene product function.
Gregory MA, Hong H, Lill RE, Gaisser S, Petkovic H, Low L, Sheehan LS, Carletti I, Ready SJ, Ward MJ, Kaja AL, Weston AJ, Challis IR, Leadlay PF, Martin CJ, Wilkinson B, Sheridan RM. Gregory MA, et al. Among authors: petkovic h. Org Biomol Chem. 2006 Oct 7;4(19):3565-8. doi: 10.1039/b608813a. Epub 2006 Aug 22. Org Biomol Chem. 2006. PMID: 16990929
Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus.
Gregory MA, Gaisser S, Lill RE, Hong H, Sheridan RM, Wilkinson B, Petkovic H, Weston AJ, Carletti I, Lee HL, Staunton J, Leadlay PF. Gregory MA, et al. Among authors: petkovic h. Angew Chem Int Ed Engl. 2004 May 3;43(19):2551-3. doi: 10.1002/anie.200453764. Angew Chem Int Ed Engl. 2004. PMID: 15127450 No abstract available.
Active-site residue, domain and module swaps in modular polyketide synthases.
Del Vecchio F, Petkovic H, Kendrew SG, Low L, Wilkinson B, Lill R, Cortés J, Rudd BA, Staunton J, Leadlay PF. Del Vecchio F, et al. Among authors: petkovic h. J Ind Microbiol Biotechnol. 2003 Aug;30(8):489-94. doi: 10.1007/s10295-003-0062-0. Epub 2003 Jun 14. J Ind Microbiol Biotechnol. 2003. PMID: 12811585
Novel chemobiosynthetic approach for exclusive production of FK506.
Kosec G, Goranovič D, Mrak P, Fujs S, Kuščer E, Horvat J, Kopitar G, Petković H. Kosec G, et al. Among authors: petkovic h. Metab Eng. 2012 Jan;14(1):39-46. doi: 10.1016/j.ymben.2011.11.003. Epub 2011 Nov 12. Metab Eng. 2012. PMID: 22100790
53 results