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Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase gamma.
Pomel V, Klicic J, Covini D, Church DD, Shaw JP, Roulin K, Burgat-Charvillon F, Valognes D, Camps M, Chabert C, Gillieron C, Françon B, Perrin D, Leroy D, Gretener D, Nichols A, Vitte PA, Carboni S, Rommel C, Schwarz MK, Rückle T. Pomel V, et al. Among authors: perrin d. J Med Chem. 2006 Jun 29;49(13):3857-71. doi: 10.1021/jm0601598. J Med Chem. 2006. PMID: 16789742
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis.
Camps M, Rückle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Françon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C. Camps M, et al. Among authors: perrin d. Nat Med. 2005 Sep;11(9):936-43. doi: 10.1038/nm1284. Epub 2005 Aug 28. Nat Med. 2005. PMID: 16127437 Free article.
GLEPP1/protein-tyrosine phosphatase phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis.
Gobert RP, van den Eijnden M, Szyndralewiez C, Jorand-Lebrun C, Swinnen D, Chen L, Gillieron C, Pixley F, Juillard P, Gerber P, Johnson-Léger C, Halazy S, Camps M, Bombrun A, Shipp M, Vitte PA, Ardissone V, Ferrandi C, Perrin D, Rommel C, Hooft van Huijsduijnen R. Gobert RP, et al. Among authors: perrin d. J Biol Chem. 2009 Apr 24;284(17):11385-95. doi: 10.1074/jbc.M807241200. Epub 2009 Feb 20. J Biol Chem. 2009. PMID: 19233845 Free PMC article.
Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Gobert RP, Joubert L, Curchod ML, Salvat C, Foucault I, Jorand-Lebrun C, Lamarine M, Peixoto H, Vignaud C, Frémaux C, Jomotte T, Françon B, Alliod C, Bernasconi L, Abderrahim H, Perrin D, Bombrun A, Zanoguera F, Rommel C, Hooft van Huijsduijnen R. Gobert RP, et al. Among authors: perrin d. Mol Cell Biol. 2009 Mar;29(6):1538-53. doi: 10.1128/MCB.01375-08. Epub 2009 Jan 12. Mol Cell Biol. 2009. PMID: 19139271 Free PMC article.
In vitro and in vivo pharmacological profile of AS057278, a selective d-amino acid oxidase inhibitor with potential anti-psychotic properties.
Adage T, Trillat AC, Quattropani A, Perrin D, Cavarec L, Shaw J, Guerassimenko O, Giachetti C, Gréco B, Chumakov I, Halazy S, Roach A, Zaratin P. Adage T, et al. Among authors: perrin d. Eur Neuropsychopharmacol. 2008 Mar;18(3):200-14. doi: 10.1016/j.euroneuro.2007.06.006. Epub 2007 Aug 2. Eur Neuropsychopharmacol. 2008. PMID: 17681761
596 results