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3,4-Dihydro-1,3,5-triazin-2(1H)-ones as the First Dual BACE-1/GSK-3β Fragment Hits against Alzheimer's Disease.
Prati F, De Simone A, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Bertozzi SM, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Sabatino P, Bottegoni G, Martinez A, Cavalli A, Bolognesi ML. Prati F, et al. Among authors: perez castillo a, perez di. ACS Chem Neurosci. 2015 Oct 21;6(10):1665-82. doi: 10.1021/acschemneuro.5b00121. Epub 2015 Aug 3. ACS Chem Neurosci. 2015. PMID: 26171616 Free article.
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets.
Chlebek J, De Simone A, Hošťálková A, Opletal L, Pérez C, Pérez DI, Havlíková L, Cahlíková L, Andrisano V. Chlebek J, et al. Among authors: perez di, perez c. Fitoterapia. 2016 Mar;109:241-7. doi: 10.1016/j.fitote.2016.01.008. Epub 2016 Jan 11. Fitoterapia. 2016. PMID: 26779945 Free article.
In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier.
Chlebek J, Korábečný J, Doležal R, Štěpánková Š, Pérez DI, Hošťálková A, Opletal L, Cahlíková L, Macáková K, Kučera T, Hrabinová M, Jun D. Chlebek J, et al. Among authors: perez di. Molecules. 2019 Apr 5;24(7):1340. doi: 10.3390/molecules24071340. Molecules. 2019. PMID: 30959739 Free PMC article.
A Fluorescent Styrylquinoline with Combined Therapeutic and Diagnostic Activities against Alzheimer's and Prion Diseases.
Staderini M, Aulić S, Bartolini M, Tran HN, González-Ruiz V, Pérez DI, Cabezas N, Martínez A, Martín MA, Andrisano V, Legname G, Menéndez JC, Bolognesi ML. Staderini M, et al. Among authors: perez di. ACS Med Chem Lett. 2012 Dec 28;4(2):225-9. doi: 10.1021/ml3003605. eCollection 2013 Feb 14. ACS Med Chem Lett. 2012. PMID: 24900645 Free PMC article.
Multitarget drug discovery for Alzheimer's disease: triazinones as BACE-1 and GSK-3β inhibitors.
Prati F, De Simone A, Bisignano P, Armirotti A, Summa M, Pizzirani D, Scarpelli R, Perez DI, Andrisano V, Perez-Castillo A, Monti B, Massenzio F, Polito L, Racchi M, Favia AD, Bottegoni G, Martinez A, Bolognesi ML, Cavalli A. Prati F, et al. Among authors: perez castillo a, perez di. Angew Chem Int Ed Engl. 2015 Jan 26;54(5):1578-82. doi: 10.1002/anie.201410456. Epub 2014 Dec 11. Angew Chem Int Ed Engl. 2015. PMID: 25504761 Free article.
64 results