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The type III effectors NleE and NleB from enteropathogenic E. coli and OspZ from Shigella block nuclear translocation of NF-kappaB p65.
Newton HJ, Pearson JS, Badea L, Kelly M, Lucas M, Holloway G, Wagstaff KM, Dunstone MA, Sloan J, Whisstock JC, Kaper JB, Robins-Browne RM, Jans DA, Frankel G, Phillips AD, Coulson BS, Hartland EL. Newton HJ, et al. Among authors: pearson js. PLoS Pathog. 2010 May 13;6(5):e1000898. doi: 10.1371/journal.ppat.1000898. PLoS Pathog. 2010. PMID: 20485572 Free PMC article.
A type III effector antagonizes death receptor signalling during bacterial gut infection.
Pearson JS, Giogha C, Ong SY, Kennedy CL, Kelly M, Robinson KS, Lung TW, Mansell A, Riedmaier P, Oates CV, Zaid A, Mühlen S, Crepin VF, Marches O, Ang CS, Williamson NA, O'Reilly LA, Bankovacki A, Nachbur U, Infusini G, Webb AI, Silke J, Strasser A, Frankel G, Hartland EL. Pearson JS, et al. Nature. 2013 Sep 12;501(7466):247-51. doi: 10.1038/nature12524. Nature. 2013. PMID: 24025841 Free PMC article.
Inhibition of death receptor signaling by bacterial gut pathogens.
Giogha C, Lung TW, Pearson JS, Hartland EL. Giogha C, et al. Among authors: pearson js. Cytokine Growth Factor Rev. 2014 Apr;25(2):235-43. doi: 10.1016/j.cytogfr.2013.12.012. Epub 2013 Dec 25. Cytokine Growth Factor Rev. 2014. PMID: 24440054 Review.
92 results