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Activating cannabinoid receptor 2 preserves axonal health through GSK-3β/NRF2 axis in adrenoleukodystrophy.
Parameswaran J, Goicoechea L, Planas-Serra L, Pastor A, Ruiz M, Calingasan NY, Guilera C, Aso E, Boada J, Pamplona R, Portero-Otín M, de la Torre R, Ferrer I, Casasnovas C, Pujol A, Fourcade S. Parameswaran J, et al. Acta Neuropathol. 2022 Aug;144(2):241-258. doi: 10.1007/s00401-022-02451-2. Epub 2022 Jul 1. Acta Neuropathol. 2022. PMID: 35778568
ALS-linked KIF5A ΔExon27 mutant causes neuronal toxicity through gain-of-function.
Pant DC, Parameswaran J, Rao L, Loss I, Chilukuri G, Parlato R, Shi L, Glass JD, Bassell GJ, Koch P, Yilmaz R, Weishaupt JH, Gennerich A, Jiang J. Pant DC, et al. Among authors: parameswaran j. EMBO Rep. 2022 Aug 3;23(8):e54234. doi: 10.15252/embr.202154234. Epub 2022 Jun 23. EMBO Rep. 2022. PMID: 35735139 Free PMC article.
RNA-mediated toxicity in C9orf72 ALS and FTD.
McEachin ZT, Parameswaran J, Raj N, Bassell GJ, Jiang J. McEachin ZT, et al. Among authors: parameswaran j. Neurobiol Dis. 2020 Nov;145:105055. doi: 10.1016/j.nbd.2020.105055. Epub 2020 Aug 21. Neurobiol Dis. 2020. PMID: 32829028 Free PMC article. Review.
The peroxisomal fatty acid transporter ABCD1/PMP-4 is required in the C. elegans hypodermis for axonal maintenance: A worm model for adrenoleukodystrophy.
Coppa A, Guha S, Fourcade S, Parameswaran J, Ruiz M, Moser AB, Schlüter A, Murphy MP, Lizcano JM, Miranda-Vizuete A, Dalfó E, Pujol A. Coppa A, et al. Among authors: parameswaran j. Free Radic Biol Med. 2020 May 20;152:797-809. doi: 10.1016/j.freeradbiomed.2020.01.177. Epub 2020 Feb 1. Free Radic Biol Med. 2020. PMID: 32017990 Free PMC article.
Rare variants in MYH15 modify amyotrophic lateral sclerosis risk.
Kim H, Lim J, Bao H, Jiao B, Canon SM, Epstein MP, Xu K, Jiang J, Parameswaran J, Li Y, Moberg KH, Landers JE, Fournier C, Allen EG, Glass JD, Wingo TS, Jin P. Kim H, et al. Among authors: parameswaran j. Hum Mol Genet. 2019 Jul 15;28(14):2309-2318. doi: 10.1093/hmg/ddz063. Hum Mol Genet. 2019. PMID: 30985904 Free PMC article.
Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.
Lee JW, Parameswaran J, Sandoval-Schaefer T, Eoh KJ, Yang DH, Zhu F, Mehra R, Sharma R, Gaffney SG, Perry EB, Townsend JP, Serebriiskii IG, Golemis EA, Issaeva N, Yarbrough WG, Koo JS, Burtness B. Lee JW, et al. Among authors: parameswaran j. Clin Cancer Res. 2019 Jun 1;25(11):3430-3442. doi: 10.1158/1078-0432.CCR-18-0440. Epub 2019 Feb 12. Clin Cancer Res. 2019. PMID: 30755439 Free PMC article.
Patient-Specific iPSC-Derived Astrocytes Contribute to Non-Cell-Autonomous Neurodegeneration in Parkinson's Disease.
di Domenico A, Carola G, Calatayud C, Pons-Espinal M, Muñoz JP, Richaud-Patin Y, Fernandez-Carasa I, Gut M, Faella A, Parameswaran J, Soriano J, Ferrer I, Tolosa E, Zorzano A, Cuervo AM, Raya A, Consiglio A. di Domenico A, et al. Among authors: parameswaran j. Stem Cell Reports. 2019 Feb 12;12(2):213-229. doi: 10.1016/j.stemcr.2018.12.011. Epub 2019 Jan 10. Stem Cell Reports. 2019. PMID: 30639209 Free PMC article.
15 results