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Design and Synthesis of Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors - In vitro Evaluation of their Antiproliferative Activity.
Batsi Y, Antonopoulou G, Fotopoulou T, Koumaki K, Kritsi E, Potamitis C, Goulielmaki M, Skarmalioraki S, Papalouka C, Poulou-Sidiropoulou E, Kosmidou V, Douna S, Vidali MS, Gkotsi EF, Chatziioannou A, Souliotis VL, Pletsa V, Papadodima O, Zoumpourlis V, Georgiadis P, Zervou M, Pintzas A, Kostas ID. Batsi Y, et al. Among authors: papadodima o. ChemMedChem. 2023 Nov 16;18(22):e202300322. doi: 10.1002/cmdc.202300322. Epub 2023 Oct 24. ChemMedChem. 2023. PMID: 37792577
BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
Koumaki K, Kontogianni G, Kosmidou V, Pahitsa F, Kritsi E, Zervou M, Chatziioannou A, Souliotis VL, Papadodima O, Pintzas A. Koumaki K, et al. Among authors: papadodima o. Biochim Biophys Acta Mol Basis Dis. 2021 Apr 1;1867(4):166061. doi: 10.1016/j.bbadis.2020.166061. Epub 2020 Dec 29. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33385518 Free article.
ERβ1 Sensitizes and ERβ2 Desensitizes ERα-Positive Breast Cancer Cells to the Inhibitory Effects of Tamoxifen, Fulvestrant and Their Combination with All-Trans Retinoic Acid.
Meligova AK, Siakouli D, Stasinopoulou S, Xenopoulou DS, Zoumpouli M, Ganou V, Gkotsi EF, Chatziioannou A, Papadodima O, Pilalis E, Alexis MN, Mitsiou DJ. Meligova AK, et al. Among authors: papadodima o. Int J Mol Sci. 2023 Feb 13;24(4):3747. doi: 10.3390/ijms24043747. Int J Mol Sci. 2023. PMID: 36835157 Free PMC article.
Novel pyrazolopyridine derivatives as potential angiogenesis inhibitors: Synthesis, biological evaluation and transcriptome-based mechanistic analysis.
Michailidou M, Giannouli V, Kotsikoris V, Papadodima O, Kontogianni G, Kostakis IK, Lougiakis N, Chatziioannou A, Kolisis FN, Marakos P, Pouli N, Loutrari H. Michailidou M, et al. Among authors: papadodima o. Eur J Med Chem. 2016 Oct 4;121:143-157. doi: 10.1016/j.ejmech.2016.05.035. Epub 2016 May 20. Eur J Med Chem. 2016. PMID: 27240270
23 results