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Insights into PPARγ Phosphorylation and Its Inhibition Mechanism.
Montanari R, Capelli D, Yamamoto K, Awaishima H, Nishikata K, Barendregt A, Heck AJR, Loiodice F, Altieri F, Paiardini A, Grottesi A, Pirone L, Pedone E, Peiretti F, Brunel JM, Itoh T, Pochetti G. Montanari R, et al. Among authors: paiardini a. J Med Chem. 2020 May 14;63(9):4811-4823. doi: 10.1021/acs.jmedchem.0c00048. Epub 2020 Apr 15. J Med Chem. 2020. PMID: 32239932 Free article.
AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
Asteriti IA, Polverino F, Stagni V, Sterbini V, Ascanelli C, Naso FD, Mastrangelo A, Rosa A, Paiardini A, Lindon C, Guarguaglini G. Asteriti IA, et al. Among authors: paiardini a. Life Sci Alliance. 2023 Feb 16;6(5):e202201726. doi: 10.26508/lsa.202201726. Print 2023 May. Life Sci Alliance. 2023. PMID: 36797043 Free PMC article.
A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression.
Di Nisio E, Licursi V, Mannironi C, Buglioni V, Paiardini A, Robusti G, Noberini R, Bonaldi T, Negri R. Di Nisio E, et al. Among authors: paiardini a. Cancer Gene Ther. 2023 Jun;30(6):822-832. doi: 10.1038/s41417-022-00584-w. Epub 2023 Jan 26. Cancer Gene Ther. 2023. PMID: 36697763 Free PMC article.
Structural investigation of nucleophosmin interaction with the tumor suppressor Fbw7γ.
Di Matteo A, Franceschini M, Paiardini A, Grottesi A, Chiarella S, Rocchio S, Di Natale C, Marasco D, Vitagliano L, Travaglini-Allocatelli C, Federici L. Di Matteo A, et al. Among authors: paiardini a. Oncogenesis. 2017 Sep 18;6(9):e379. doi: 10.1038/oncsis.2017.78. Oncogenesis. 2017. PMID: 28920929 Free PMC article.
128 results