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Synthesis of fluorinated purine and 1-deazapurine glycosides as potential inhibitors of adenosine deaminase.
J Org Chem. 2011 Apr 15;76(8):2899-903. doi: 10.1021/jo102579g. Epub 2011 Mar 23.
J Org Chem. 2011.
PMID: 21395333
3-Methoxalylchromone--a novel versatile reagent for the regioselective purine isostere synthesis.
Mkrtchyan S, Iaroshenko VO, Dudkin S, Gevorgyan A, Vilches-Herrera M, Ghazaryan G, Volochnyuk DM, Ostrovskyi D, Ahmed Z, Villinger A, Sosnovskikh VY, Langer P.
Mkrtchyan S, et al. Among authors: ostrovskyi d.
Org Biomol Chem. 2010 Dec 7;8(23):5280-4. doi: 10.1039/c0ob00379d. Epub 2010 Oct 11.
Org Biomol Chem. 2010.
PMID: 20938501
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4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1).
Hügle M, Lucas X, Weitzel G, Ostrovskyi D, Breit B, Gerhardt S, Einsle O, Günther S, Wohlwend D.
Hügle M, et al. Among authors: ostrovskyi d.
J Med Chem. 2016 Feb 25;59(4):1518-30. doi: 10.1021/acs.jmedchem.5b01267. Epub 2016 Jan 14.
J Med Chem. 2016.
PMID: 26731611
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Total synthesis of (18S)- and (18R)-homolargazole by rhodium-catalyzed hydrocarboxylation.
Schotes C, Ostrovskyi D, Senger J, Schmidtkunz K, Jung M, Breit B.
Schotes C, et al. Among authors: ostrovskyi d.
Chemistry. 2014 Feb 17;20(8):2164-8. doi: 10.1002/chem.201303300. Epub 2014 Jan 29.
Chemistry. 2014.
PMID: 24478039
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Preparation data of the bromodomains BRD3(1), BRD3(2), BRD4(1), and BRPF1B and crystallization of BRD4(1)-inhibitor complexes.
Hügle M, Lucas X, Weitzel G, Ostrovskyi D, Breit B, Gerhardt S, Schmidtkunz K, Jung M, Schüle R, Einsle O, Günther S, Wohlwend D.
Hügle M, et al. Among authors: ostrovskyi d.
Data Brief. 2016 Apr 11;7:1370-4. doi: 10.1016/j.dib.2016.04.009. eCollection 2016 Jun.
Data Brief. 2016.
PMID: 27158652
Free PMC article.
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Beyond the BET Family: Targeting CBP/p300 with 4-Acyl Pyrroles.
Hügle M, Lucas X, Ostrovskyi D, Regenass P, Gerhardt S, Einsle O, Hau M, Jung M, Breit B, Günther S, Wohlwend D.
Hügle M, et al. Among authors: ostrovskyi d.
Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12476-12480. doi: 10.1002/anie.201705516. Epub 2017 Sep 7.
Angew Chem Int Ed Engl. 2017.
PMID: 28766825
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Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors.
Luise C, Robaa D, Regenass P, Maurer D, Ostrovskyi D, Seifert L, Bacher J, Burgahn T, Wagner T, Seitz J, Greschik H, Park KS, Xiong Y, Jin J, Schüle R, Breit B, Jung M, Sippl W.
Luise C, et al. Among authors: ostrovskyi d.
Int J Mol Sci. 2021 May 31;22(11):5910. doi: 10.3390/ijms22115910.
Int J Mol Sci. 2021.
PMID: 34072837
Free PMC article.
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Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1).
Ostrovskyi D, Rumpf T, Eib J, Lumbroso A, Slynko I, Klaeger S, Heinzlmeir S, Forster M, Gehringer M, Pfaffenrot E, Bauer SM, Schmidtkunz K, Wenzler S, Metzger E, Kuster B, Laufer S, Schüle R, Sippl W, Breit B, Jung M.
Ostrovskyi D, et al.
Future Med Chem. 2016 Sep;8(13):1537-51. doi: 10.4155/fmc-2016-0132. Epub 2016 Aug 30.
Future Med Chem. 2016.
PMID: 27572962
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