3-Methoxalylchromone--a novel versatile reagent for the regioselective purine isostere synthesis

Org Biomol Chem. 2010 Dec 7;8(23):5280-4. doi: 10.1039/c0ob00379d. Epub 2010 Oct 11.

Abstract

The first synthesis of 3-methoxalylchromone was described. The reaction of the latter with electron-rich aminoheterocycles afforded a set of heteroannelated pyridines bearing a CO(2)Me substituent located at the α-position of the pyridine core.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromones / chemical synthesis*
  • Models, Molecular
  • Molecular Structure
  • Purines / chemistry*

Substances

  • 3-methoxalylchromone
  • Chromones
  • Purines
  • purine