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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors.
Wilkinson AJ, Ooi N, Finlayson J, Lee VE, Lyth D, Maskew KS, Newman R, Orr D, Ansell K, Birchall K, Canning P, Coombs P, Fusani L, McIver E, Pisco J, Ireland PM, Jenkins C, Norville IH, Southern SJ, Cowan R, Hall G, Kettleborough C, Savage VJ, Cooper IR. Wilkinson AJ, et al. Among authors: orr d. Bioorg Med Chem Lett. 2023 Jun 15;90:129331. doi: 10.1016/j.bmcl.2023.129331. Epub 2023 May 13. Bioorg Med Chem Lett. 2023. PMID: 37187252 Free article.
Purification of Rubisco from Leaves.
Amaral J, Lobo AKM, Carmo-Silva E, Orr DJ. Amaral J, et al. Among authors: orr dj. Methods Mol Biol. 2024;2790:417-426. doi: 10.1007/978-1-0716-3790-6_22. Methods Mol Biol. 2024. PMID: 38649584
Extraction of Soluble Proteins from Leaves.
Carmo-Silva E, Page R, Marsden CJ, Gjindali A, Orr DJ. Carmo-Silva E, et al. Among authors: orr dj. Methods Mol Biol. 2024;2790:391-404. doi: 10.1007/978-1-0716-3790-6_20. Methods Mol Biol. 2024. PMID: 38649582
A multicenter, randomized phase 2 study to establish combinations of CBP501, cisplatin and nivolumab for ≥3rd-line treatment of patients with advanced pancreatic adenocarcinoma.
Enzler T, Nguyen A, Misleh J, Cline VJ, Johns M, Shumway N, Paulson S, Siegel R, Larson T, Messersmith W, Richards D, Chaves J, Pierce E, Zalupski M, Sahai V, Orr D, Ruste SA, Haun A, Kawabe T. Enzler T, et al. Among authors: orr d. Eur J Cancer. 2024 Apr;201:113950. doi: 10.1016/j.ejca.2024.113950. Epub 2024 Feb 22. Eur J Cancer. 2024. PMID: 38422585 Free article. Clinical Trial.
560 results