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RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival.
Novak R, Ahmad YA, Timaner M, Bitman-Lotan E, Oknin-Vaisman A, Horwitz R, Hartmann O, Reissland M, Buck V, Rosenfeldt M, Nikomarov D, Diefenbacher ME, Shaked Y, Orian A. Novak R, et al. Among authors: orian a. Cell Death Dis. 2022 Sep 24;13(9):820. doi: 10.1038/s41419-022-05262-1. Cell Death Dis. 2022. PMID: 36153321 Free PMC article.
A fly view of a SUMO-targeted ubiquitin ligase.
Abed M, Bitman-Lotan E, Orian A. Abed M, et al. Among authors: orian a. Fly (Austin). 2011 Oct-Dec;5(4):340-4. doi: 10.4161/fly.5.4.17608. Epub 2011 Aug 22. Fly (Austin). 2011. PMID: 21857164
RNF4-Dependent Oncogene Activation by Protein Stabilization.
Thomas JJ, Abed M, Heuberger J, Novak R, Zohar Y, Beltran Lopez AP, Trausch-Azar JS, Ilagan MXG, Benhamou D, Dittmar G, Kopan R, Birchmeier W, Schwartz AL, Orian A. Thomas JJ, et al. Among authors: orian a. Cell Rep. 2016 Sep 20;16(12):3388-3400. doi: 10.1016/j.celrep.2016.08.024. Cell Rep. 2016. PMID: 27653698 Free PMC article.
Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells.
Prieto-Garcia C, Hartmann O, Reissland M, Braun F, Fischer T, Walz S, Schülein-Völk C, Eilers U, Ade CP, Calzado MA, Orian A, Maric HM, Münch C, Rosenfeldt M, Eilers M, Diefenbacher ME. Prieto-Garcia C, et al. Among authors: orian a. EMBO Mol Med. 2020 Apr 7;12(4):e11101. doi: 10.15252/emmm.201911101. Epub 2020 Mar 4. EMBO Mol Med. 2020. PMID: 32128997 Free PMC article.
Regulation of eIF2α by RNF4 Promotes Melanoma Tumorigenesis and Therapy Resistance.
Avitan-Hersh E, Feng Y, Oknin Vaisman A, Abu Ahmad Y, Zohar Y, Zhang T, Lee JS, Lazar I, Sheikh Khalil S, Feiler Y, Kluger H, Kahana C, Brown K, Ruppin E, Ronai ZA, Orian A. Avitan-Hersh E, et al. Among authors: orian a. J Invest Dermatol. 2020 Dec;140(12):2466-2477. doi: 10.1016/j.jid.2020.04.008. Epub 2020 Apr 29. J Invest Dermatol. 2020. PMID: 32360601 Free PMC article.
Nuclear organization and regulation of the differentiated state.
Bitman-Lotan E, Orian A. Bitman-Lotan E, et al. Among authors: orian a. Cell Mol Life Sci. 2021 Apr;78(7):3141-3158. doi: 10.1007/s00018-020-03731-4. Epub 2021 Jan 28. Cell Mol Life Sci. 2021. PMID: 33507327 Free PMC article. Review.
51 results