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A variant in human AIOLOS impairs adaptive immunity by interfering with IKAROS.
Yamashita M, Kuehn HS, Okuyama K, Okada S, Inoue Y, Mitsuiki N, Imai K, Takagi M, Kanegane H, Takeuchi M, Shimojo N, Tsumura M, Padhi AK, Zhang KYJ, Boisson B, Casanova JL, Ohara O, Rosenzweig SD, Taniuchi I, Morio T. Yamashita M, et al. Among authors: okuyama k. Nat Immunol. 2021 Jul;22(7):893-903. doi: 10.1038/s41590-021-00951-z. Epub 2021 Jun 21. Nat Immunol. 2021. PMID: 34155405 Free PMC article.
T and B cell abnormalities, pneumocystis pneumonia, and chronic lymphocytic leukemia associated with an AIOLOS defect in patients.
Kuehn HS, Chang J, Yamashita M, Niemela JE, Zou C, Okuyama K, Harada J, Stoddard JL, Nunes-Santos CJ, Boast B, Baxter RM, Hsieh EWY, Garofalo M, Fleisher TA, Morio T, Taniuchi I, Dutmer CM, Rosenzweig SD. Kuehn HS, et al. Among authors: okuyama k. J Exp Med. 2021 Dec 6;218(12):e20211118. doi: 10.1084/jem.20211118. Epub 2021 Oct 25. J Exp Med. 2021. PMID: 34694366 Free PMC article.
A Notch ligand, Delta-like 1 functions as an adhesion molecule for mast cells.
Murata A, Okuyama K, Sakano S, Kajiki M, Hirata T, Yagita H, Zúñiga-Pflücker JC, Miyake K, Akashi-Takamura S, Moriwaki S, Niida S, Yoshino M, Hayashi S. Murata A, et al. Among authors: okuyama k. J Immunol. 2010 Oct 1;185(7):3905-12. doi: 10.4049/jimmunol.1000195. Epub 2010 Sep 1. J Immunol. 2010. PMID: 20810995
PD-L1/L2 protein levels rapidly increase on monocytes via trogocytosis from tumor cells in classical Hodgkin lymphoma.
Kawashima M, Carreras J, Higuchi H, Kotaki R, Hoshina T, Okuyama K, Suzuki N, Kakizaki M, Miyatake Y, Ando K, Nakayama M, Umezu S, Horie R, Higuchi Y, Katagiri K, Goyama S, Kitamura T, Chamoto K, Yano S, Nakamura N, Kotani A. Kawashima M, et al. Among authors: okuyama k. Leukemia. 2020 Sep;34(9):2405-2417. doi: 10.1038/s41375-020-0737-9. Epub 2020 Feb 24. Leukemia. 2020. PMID: 32089543
Overexpression of miR-669m inhibits erythroblast differentiation.
Kotaki R, Kawashima M, Yamaguchi A, Suzuki N, Koyama-Nasu R, Ogiya D, Okuyama K, Yamamoto Y, Takamatsu M, Kurosaki N, Ando K, Murata A, Ohtsuka M, Nakagawa S, Katagiri K, Kotani A. Kotaki R, et al. Among authors: okuyama k. Sci Rep. 2020 Aug 11;10(1):13554. doi: 10.1038/s41598-020-70442-y. Sci Rep. 2020. PMID: 32782283 Free PMC article.
MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors.
Okuyama K, Ikawa T, Gentner B, Hozumi K, Harnprasopwat R, Lu J, Yamashita R, Ha D, Toyoshima T, Chanda B, Kawamata T, Yokoyama K, Wang S, Ando K, Lodish HF, Tojo A, Kawamoto H, Kotani A. Okuyama K, et al. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13410-5. doi: 10.1073/pnas.1220710110. Epub 2013 Jul 26. Proc Natl Acad Sci U S A. 2013. PMID: 23893300 Free PMC article.
717 results