Okada T - Search Results

1

Anti-Austerity Activity of Thai Medicinal Plants: Chemical Constituents and Anti-Pancreatic Cancer Activities of Kaempferia parviflora.

Sun S, Kim MJ, Dibwe DF, Omar AM, Athikomkulchai S, Phrutivorapongkul A, Okada T, Tsuge K, Toyooka N, Awale S. Sun S, et al. Among authors: okada t. Plants (Basel). 2021 Jan 25;10(2):229. doi: 10.3390/plants10020229. Plants (Basel). 2021. PMID: 33503922 Free PMC article.

2

Design and synthesis of functionalized coumarins as potential anti-austerity agents that eliminates cancer cells' tolerance to nutrition starvation.

Awale S, Okada T, Dibwe DF, Maruyama T, Takahara S, Okada T, Endo S, Toyooka N. Awale S, et al. Among authors: okada t. Bioorg Med Chem Lett. 2019 Jul 15;29(14):1779-1784. doi: 10.1016/j.bmcl.2019.05.010. Epub 2019 May 8. Bioorg Med Chem Lett. 2019. PMID: 31097375

3

Design and synthesis of novel pipernonaline derivatives as anti-austerity agents against human pancreatic cancer PANC-1 cells.

Okada T, Chino Y, Yokoyama K, Fujihashi Y, Duy Phan N, Maneenet J, Prudhvi L, Awale S, Toyooka N. Okada T, et al. Bioorg Med Chem. 2022 Oct 1;71:116963. doi: 10.1016/j.bmc.2022.116963. Epub 2022 Aug 10. Bioorg Med Chem. 2022. PMID: 35969895

4

Discovery of novel adenylyl cyclase inhibitor by cell-based screening.

Mano H, Ishimoto T, Okada T, Toyooka N, Mori H. Mano H, et al. Among authors: okada t. Biol Pharm Bull. 2014;37(10):1689-93. doi: 10.1248/bpb.b14-00283. Biol Pharm Bull. 2014. PMID: 25273392 Free article.

5

Total Synthesis of Decahydroquinoline Poison Frog Alkaloids ent-cis-195A and cis-211A.

Okada T, Wu N, Takashima K, Ishimura J, Morita H, Ito T, Kodama T, Yamasaki Y, Akanuma SI, Kubo Y, Hosoya KI, Tsuneki H, Wada T, Sasaoka T, Shimizu T, Sakai H, Dwoskin LP, Hussaini SR, Saporito RA, Toyooka N. Okada T, et al. Molecules. 2021 Dec 12;26(24):7529. doi: 10.3390/molecules26247529. Molecules. 2021. PMID: 34946611 Free PMC article.

6

Synthesis of new tricyclic thiolactams as potent antitumor agent for pancreatic cancer.

Okada T, Minehira D, Takada M, Urata H, Kato A, Adachi I, Kurashima Y, Kaji S, Ogura T, Chiba S, Esumi H, Toyooka N. Okada T, et al. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2577-9. doi: 10.1016/j.bmcl.2016.04.035. Epub 2016 Apr 16. Bioorg Med Chem Lett. 2016. PMID: 27117432

7

Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.

Kudo Y, Endo S, Fujita M, Ota A, Kamatari YO, Tanaka Y, Ishikawa T, Ikeda H, Okada T, Toyooka N, Fujimoto N, Matsunaga T, Ikari A. Kudo Y, et al. Among authors: okada t. J Med Chem. 2022 Mar 24;65(6):4878-4892. doi: 10.1021/acs.jmedchem.1c02113. Epub 2022 Mar 4. J Med Chem. 2022. PMID: 35244402

8

Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.

Kitakami R, Inui K, Nakagawa Y, Sawai Y, Katayama W, Yokoyama T, Okada T, Kanamitsu K, Nakagawa S, Toyooka N, Mizuguchi M. Kitakami R, et al. Among authors: okada t. Bioorg Med Chem. 2021 Aug 15;44:116292. doi: 10.1016/j.bmc.2021.116292. Epub 2021 Jun 26. Bioorg Med Chem. 2021. PMID: 34225167

9

A New Method for Albuminuria Measurement Using a Specific Reaction between Albumin and the Luciferin of the Firefly Squid Watasenia scintillans.

Ishimoto T, Okada T, Fujisaka S, Yagi K, Tobe K, Toyooka N, Mori H. Ishimoto T, et al. Among authors: okada t. Int J Mol Sci. 2022 Jul 28;23(15):8342. doi: 10.3390/ijms23158342. Int J Mol Sci. 2022. PMID: 35955470 Free PMC article.

10

Identification and Total Synthesis of Two Previously Unreported Odd-Chain Bis-Methylene-Interrupted Fatty Acids with a Terminal Olefin that Activate Protein Phosphatase, Mg²⁺/Mn²⁺-Dependent 1A (PPM1A) in Ovaries of the Limpet Cellana toreuma.

Kawashima H, Toyooka N, Okada T, Nguyen HD, Nishikawa Y, Miura Y, Inoue N, Kimura KI. Kawashima H, et al. Among authors: okada t. Mar Drugs. 2019 Jul 11;17(7):410. doi: 10.3390/md17070410. Mar Drugs. 2019. PMID: 31336763 Free PMC article.

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