Ohoka N - Search Results

1

Structure-Activity Relationship Study of Helix-Stabilized Antimicrobial Peptides Containing Nonproteinogenic Amino Acids.

Ito T, Hashimoto W, Ohoka N, Misawa T, Inoue T, Kawano R, Demizu Y. Ito T, et al. Among authors: ohoka n. ACS Biomater Sci Eng. 2023 Aug 14;9(8):4654-4661. doi: 10.1021/acsbiomaterials.3c00759. Epub 2023 Jul 24. ACS Biomater Sci Eng. 2023. PMID: 37486982

2

Development of hybrid small molecules that induce degradation of estrogen receptor-alpha and necrotic cell death in breast cancer cells.

Okuhira K, Demizu Y, Hattori T, Ohoka N, Shibata N, Nishimaki-Mogami T, Okuda H, Kurihara M, Naito M. Okuhira K, et al. Among authors: ohoka n. Cancer Sci. 2013 Nov;104(11):1492-8. doi: 10.1111/cas.12272. Epub 2013 Oct 11. Cancer Sci. 2013. PMID: 23992566 Free PMC article.

3

Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton.

Misawa T, Yorioka M, Demizu Y, Noguchi-Yachide T, Ohoka N, Kurashima-Kinoshita M, Motoyoshi H, Nojiri H, Kittaka A, Makishima M, Naito M, Kurihara M. Misawa T, et al. Among authors: ohoka n. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5362-6. doi: 10.1016/j.bmcl.2015.09.030. Epub 2015 Sep 12. Bioorg Med Chem Lett. 2015. PMID: 26432035

4

Molecular Design, Synthesis, and Evaluation of SNIPER(ER) That Induces Proteasomal Degradation of ERα.

Okuhira K, Demizu Y, Hattori T, Ohoka N, Shibata N, Kurihara M, Naito M. Okuhira K, et al. Among authors: ohoka n. Methods Mol Biol. 2016;1366:549-560. doi: 10.1007/978-1-4939-3127-9_42. Methods Mol Biol. 2016. PMID: 26585163

5

Development of a peptide-based inducer of nuclear receptors degradation.

Demizu Y, Ohoka N, Nagakubo T, Yamashita H, Misawa T, Okuhira K, Naito M, Kurihara M. Demizu Y, et al. Among authors: ohoka n. Bioorg Med Chem Lett. 2016 Jun 1;26(11):2655-8. doi: 10.1016/j.bmcl.2016.04.013. Epub 2016 Apr 7. Bioorg Med Chem Lett. 2016. PMID: 27086122

6

Development of a Cell-penetrating Peptide that Exhibits Responsive Changes in its Secondary Structure in the Cellular Environment.

Yamashita H, Kato T, Oba M, Misawa T, Hattori T, Ohoka N, Tanaka M, Naito M, Kurihara M, Demizu Y. Yamashita H, et al. Among authors: ohoka n. Sci Rep. 2016 Sep 9;6:33003. doi: 10.1038/srep33003. Sci Rep. 2016. PMID: 27609319 Free PMC article.

7

Development of BCR-ABL degradation inducers via the conjugation of an imatinib derivative and a cIAP1 ligand.

Demizu Y, Shibata N, Hattori T, Ohoka N, Motoi H, Misawa T, Shoda T, Naito M, Kurihara M. Demizu Y, et al. Among authors: ohoka n. Bioorg Med Chem Lett. 2016 Oct 15;26(20):4865-4869. doi: 10.1016/j.bmcl.2016.09.041. Epub 2016 Sep 15. Bioorg Med Chem Lett. 2016. PMID: 27666635

8

Targeted Degradation of Proteins Localized in Subcellular Compartments by Hybrid Small Molecules.

Okuhira K, Shoda T, Omura R, Ohoka N, Hattori T, Shibata N, Demizu Y, Sugihara R, Ichino A, Kawahara H, Itoh Y, Ishikawa M, Hashimoto Y, Kurihara M, Itoh S, Saito H, Naito M. Okuhira K, et al. Among authors: ohoka n. Mol Pharmacol. 2017 Mar;91(3):159-166. doi: 10.1124/mol.116.105569. Epub 2016 Dec 13. Mol Pharmacol. 2017. PMID: 27965304

9

Simple and efficient knockdown of His-tagged proteins by ternary molecules consisting of a His-tag ligand, a ubiquitin ligase ligand, and a cell-penetrating peptide.

Hattori T, Okitsu K, Yamazaki N, Ohoka N, Shibata N, Misawa T, Kurihara M, Demizu Y, Naito M. Hattori T, et al. Among authors: ohoka n. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4478-4481. doi: 10.1016/j.bmcl.2017.08.001. Epub 2017 Aug 2. Bioorg Med Chem Lett. 2017. PMID: 28807436

10

Development of a peptide-based inducer of protein degradation targeting NOTCH1.

Ohoka N, Misawa T, Kurihara M, Demizu Y, Naito M. Ohoka N, et al. Bioorg Med Chem Lett. 2017 Nov 15;27(22):4985-4988. doi: 10.1016/j.bmcl.2017.10.011. Epub 2017 Oct 7. Bioorg Med Chem Lett. 2017. PMID: 29050782

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