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Deconstructing the traditional Japanese medicine "Kampo": compounds, metabolites and pharmacological profile of maoto, a remedy for flu-like symptoms.
Nishi A, Ohbuchi K, Kushida H, Matsumoto T, Lee K, Kuroki H, Nabeshima S, Shimobori C, Komokata N, Kanno H, Tsuchiya N, Zushi M, Hattori T, Yamamoto M, Kase Y, Matsuoka Y, Kitano H. Nishi A, et al. Among authors: ohbuchi k. NPJ Syst Biol Appl. 2017 Oct 24;3:32. doi: 10.1038/s41540-017-0032-1. eCollection 2017. NPJ Syst Biol Appl. 2017. PMID: 29075514 Free PMC article.
In Vivo Pharmacokinetic Analysis Utilizing Non-Targeted and Targeted Mass Spectrometry and In Vitro Assay against Transient Receptor Potential Channels of Maobushisaishinto and Its Constituent Asiasari Radix.
Matsumoto T, Takiyama M, Sanechika S, Nakayama A, Aoki K, Ohbuchi K, Kushida H, Kanno H, Nishi A, Watanabe J. Matsumoto T, et al. Among authors: ohbuchi k. Molecules. 2020 Sep 18;25(18):4283. doi: 10.3390/molecules25184283. Molecules. 2020. PMID: 32962000 Free PMC article.
Integrated analysis of effect of daisaikoto, a traditional Japanese medicine, on the metabolome and gut microbiome in a mouse model of nonalcoholic fatty liver disease.
Ishizawa S, Nishi A, Kaifuchi N, Shimobori C, Nahata M, Yamada C, Iizuka S, Ohbuchi K, Nishiyama M, Fujitsuka N, Kono T, Yamamoto M. Ishizawa S, et al. Among authors: ohbuchi k. Gene. 2022 Dec 20;846:146856. doi: 10.1016/j.gene.2022.146856. Epub 2022 Sep 5. Gene. 2022. PMID: 36067864 Free article.
Phenotyping analysis of the Japanese Kampo medicine maoto in healthy human subjects using wide-targeted plasma metabolomics.
Kitagawa H, Ohbuchi K, Munekage M, Fujisawa K, Kawanishi Y, Namikawa T, Kushida H, Matsumoto T, Shimobori C, Nishi A, Sadakane C, Watanabe J, Yamamoto M, Hanazaki K. Kitagawa H, et al. Among authors: ohbuchi k. J Pharm Biomed Anal. 2019 Feb 5;164:119-127. doi: 10.1016/j.jpba.2018.10.026. Epub 2018 Oct 22. J Pharm Biomed Anal. 2019. PMID: 30368117 Free article. Clinical Trial.
75 results