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Page 1
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure.
Mossner M, Jann JC, Wittig J, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Boch T, Metzgeroth G, Röhl H, Witt SH, Dukal H, Klein C, Schmitt S, Gelß P, Platzbecker U, Balaian E, Fabarius A, Blum H, Schulze TJ, Meggendorfer M, Haferlach C, Trumpp A, Hofmann WK, Medyouf H, Nowak D. Mossner M, et al. Among authors: oblander j. Blood. 2016 Sep 1;128(9):1246-59. doi: 10.1182/blood-2015-11-679167. Epub 2016 Jun 6. Blood. 2016. PMID: 27268087 Free article.
Skewed X-inactivation patterns in ageing healthy and myelodysplastic haematopoiesis determined by a pyrosequencing based transcriptional clonality assay.
Mossner M, Nolte F, Hütter G, Reins J, Klaumünzer M, Nowak V, Obländer J, Ackermann K, Will S, Röhl H, Neumann U, Neumann M, Hopfer O, Baldus CD, Hofmann WK, Nowak D. Mossner M, et al. Among authors: oblander j. J Med Genet. 2013 Feb;50(2):108-17. doi: 10.1136/jmedgenet-2012-101093. J Med Genet. 2013. PMID: 23339109
Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit.
Medyouf H, Mossner M, Jann JC, Nolte F, Raffel S, Herrmann C, Lier A, Eisen C, Nowak V, Zens B, Müdder K, Klein C, Obländer J, Fey S, Vogler J, Fabarius A, Riedl E, Roehl H, Kohlmann A, Staller M, Haferlach C, Müller N, John T, Platzbecker U, Metzgeroth G, Hofmann WK, Trumpp A, Nowak D. Medyouf H, et al. Among authors: oblander j. Cell Stem Cell. 2014 Jun 5;14(6):824-37. doi: 10.1016/j.stem.2014.02.014. Epub 2014 Apr 3. Cell Stem Cell. 2014. PMID: 24704494 Free article.
Prevalence, clonal dynamics and clinical impact of TP53 mutations in patients with myelodysplastic syndrome with isolated deletion (5q) treated with lenalidomide: results from a prospective multicenter study of the german MDS study group (GMDS).
Mossner M, Jann JC, Nowak D, Platzbecker U, Giagounidis A, Götze K, Letsch A, Haase D, Shirneshan K, Braulke F, Schlenk RF, Haferlach T, Schafhausen P, Bug G, Lübbert M, Ganser A, Büsche G, Schuler E, Nowak V, Pressler J, Obländer J, Fey S, Müller N, Lauinger-Lörsch E, Metzgeroth G, Weiß C, Hofmann WK, Germing U, Nolte F. Mossner M, et al. Among authors: oblander j. Leukemia. 2016 Sep;30(9):1956-9. doi: 10.1038/leu.2016.111. Epub 2016 May 2. Leukemia. 2016. PMID: 27133825 Clinical Trial. No abstract available.
Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA.
Jann JC, Nowak D, Nolte F, Fey S, Nowak V, Obländer J, Pressler J, Palme I, Xanthopoulos C, Fabarius A, Platzbecker U, Giagounidis A, Götze K, Letsch A, Haase D, Schlenk R, Bug G, Lübbert M, Ganser A, Germing U, Haferlach C, Hofmann WK, Mossner M. Jann JC, et al. Among authors: oblander j. J Med Genet. 2017 Sep;54(9):640-650. doi: 10.1136/jmedgenet-2017-104528. Epub 2017 Jun 9. J Med Genet. 2017. PMID: 28600436 Free PMC article.
Genomic CDKN2A/2B deletions in adult Ph+ ALL are adverse despite allogeneic stem cell transplantation.
Pfeifer H, Raum K, Markovic S, Nowak V, Fey S, Obländer J, Pressler J, Böhm V, Brüggemann M, Wunderle L, Hüttmann A, Wäsch R, Beck J, Stelljes M, Viardot A, Lang F, Hoelzer D, Hofmann WK, Serve H, Weiss C, Goekbuget N, Ottmann OG, Nowak D. Pfeifer H, et al. Among authors: oblander j. Blood. 2018 Mar 29;131(13):1464-1475. doi: 10.1182/blood-2017-07-796862. Epub 2018 Jan 18. Blood. 2018. PMID: 29348129 Free article. Clinical Trial.
Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations.
Flach J, Jann JC, Knaflic A, Riabov V, Streuer A, Altrock E, Xu Q, Schmitt N, Obländer J, Nowak V, Danner J, Mehralivand A, Hofmann F, Palme I, Jawhar A, Wuchter P, Metzgeroth G, Nolte F, Hofmann WK, Nowak D. Flach J, et al. Among authors: oblander j. Haematologica. 2021 Nov 1;106(11):2906-2917. doi: 10.3324/haematol.2020.254193. Haematologica. 2021. PMID: 33054116 Free PMC article.
High erythroferrone expression in CD71+ erythroid progenitors predicts superior survival in myelodysplastic syndromes.
Riabov V, Mossner M, Stöhr A, Jann JC, Streuer A, Schmitt N, Knaflic A, Nowak V, Weimer N, Obländer J, Palme I, Schumann C, Baldus CD, Schulze TJ, Wuchter P, Röhl H, Jawhar A, Weiss C, Boch T, Metzgeroth G, Neumann M, Hofmann WK, Nolte F, Nowak D. Riabov V, et al. Among authors: oblander j. Br J Haematol. 2021 Mar;192(5):879-891. doi: 10.1111/bjh.17314. Epub 2021 Jan 24. Br J Haematol. 2021. PMID: 33486765
20 results