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Strategies towards Targeting Gαi/s Proteins: Scanning of Protein-Protein Interaction Sites To Overcome Inaccessibility.
ChemMedChem. 2021 Jun 7;16(11):1696-1715. doi: 10.1002/cmdc.202100039. Epub 2021 Mar 22.
ChemMedChem. 2021.
PMID: 33615736
Free PMC article.
Review.
Deciphering Specificity Determinants for FR900359-Derived Gq α Inhibitors Based on Computational and Structure-Activity Studies.
Reher R, Kühl T, Annala S, Benkel T, Kaufmann D, Nubbemeyer B, Odhiambo JP, Heimer P, Bäuml CA, Kehraus S, Crüsemann M, Kostenis E, Tietze D, König GM, Imhof D.
Reher R, et al. Among authors: nubbemeyer b.
ChemMedChem. 2018 Aug 20;13(16):1634-1643. doi: 10.1002/cmdc.201800304. Epub 2018 Jul 3.
ChemMedChem. 2018.
PMID: 29873888
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NMR-Based Structural Characterization of a Two-Disulfide-Bonded Analogue of the FXIIIa Inhibitor Tridegin: New Insights into Structure-Activity Relationships.
Schmitz T, Paul George AA, Nubbemeyer B, Bäuml CA, Steinmetzer T, Ohlenschläger O, Biswas A, Imhof D.
Schmitz T, et al. Among authors: nubbemeyer b.
Int J Mol Sci. 2021 Jan 17;22(2):880. doi: 10.3390/ijms22020880.
Int J Mol Sci. 2021.
PMID: 33477282
Free PMC article.
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Targeting Gαi/s Proteins with Peptidyl Nucleotide Exchange Modulators.
Nubbemeyer B, Paul George AA, Kühl T, Pepanian A, Beck MS, Maghraby R, Shetab Boushehri M, Muehlhaupt M, Pfeil EM, Annala SK, Ammer H, Imhof D, Pei D.
Nubbemeyer B, et al.
ACS Chem Biol. 2022 Feb 18;17(2):463-473. doi: 10.1021/acschembio.1c00929. Epub 2022 Jan 18.
ACS Chem Biol. 2022.
PMID: 35042325
Free PMC article.
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Bicyclic Peptide Library Screening for the Identification of Gαi Protein Modulators.
Pepanian A, Binbay FA, Roy S, Nubbemeyer B, Koley A, Rhodes CA, Ammer H, Pei D, Ghosh P, Imhof D.
Pepanian A, et al. Among authors: nubbemeyer b.
J Med Chem. 2023 Sep 14;66(17):12396-12406. doi: 10.1021/acs.jmedchem.3c00873. Epub 2023 Aug 16.
J Med Chem. 2023.
PMID: 37587416
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Mechanistic Investigations of Two Bacterial Diterpene Cyclases: Spiroviolene Synthase and Tsukubadiene Synthase.
Rabe P, Rinkel J, Dolja E, Schmitz T, Nubbemeyer B, Luu TH, Dickschat JS.
Rabe P, et al. Among authors: nubbemeyer b.
Angew Chem Int Ed Engl. 2017 Mar 1;56(10):2776-2779. doi: 10.1002/anie.201612439. Epub 2017 Jan 31.
Angew Chem Int Ed Engl. 2017.
PMID: 28146322
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Terpene Cyclases from Social Amoebae.
Rabe P, Rinkel J, Nubbemeyer B, Köllner TG, Chen F, Dickschat JS.
Rabe P, et al. Among authors: nubbemeyer b.
Angew Chem Int Ed Engl. 2016 Dec 5;55(49):15420-15423. doi: 10.1002/anie.201608971. Epub 2016 Nov 10.
Angew Chem Int Ed Engl. 2016.
PMID: 27862766
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