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Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Chen B, Scurrah CR, McKinley ET, Simmons AJ, Ramirez-Solano MA, Zhu X, Markham NO, Heiser CN, Vega PN, Rolong A, Kim H, Sheng Q, Drewes JL, Zhou Y, Southard-Smith AN, Xu Y, Ro J, Jones AL, Revetta F, Berry LD, Niitsu H, Islam M, Pelka K, Hofree M, Chen JH, Sarkizova S, Ng K, Giannakis M, Boland GM, Aguirre AJ, Anderson AC, Rozenblatt-Rosen O, Regev A, Hacohen N, Kawasaki K, Sato T, Goettel JA, Grady WM, Zheng W, Washington MK, Cai Q, Sears CL, Goldenring JR, Franklin JL, Su T, Huh WJ, Vandekar S, Roland JT, Liu Q, Coffey RJ, Shrubsole MJ, Lau KS. Chen B, et al. Among authors: niitsu h. Cell. 2021 Dec 22;184(26):6262-6280.e26. doi: 10.1016/j.cell.2021.11.031. Epub 2021 Dec 14. Cell. 2021. PMID: 34910928 Free PMC article.
Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.
Vega PN, Nilsson A, Kumar MP, Niitsu H, Simmons AJ, Ro J, Wang J, Chen Z, Joughin BA, Li W, McKinley ET, Liu Q, Roland JT, Washington MK, Coffey RJ, Lauffenburger DA, Lau KS. Vega PN, et al. Among authors: niitsu h. Front Oncol. 2022 May 4;12:878920. doi: 10.3389/fonc.2022.878920. eCollection 2022. Front Oncol. 2022. PMID: 35600339 Free PMC article.
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets.
Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ. Zhang Q, et al. Among authors: niitsu h. Nat Cell Biol. 2021 Dec;23(12):1240-1254. doi: 10.1038/s41556-021-00805-8. Epub 2021 Dec 9. Nat Cell Biol. 2021. PMID: 34887515 Free PMC article.
Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib.
Uddin MJ, Vemulapalli A, Niitsu H, Crews BC, Oltman CG, Kingsley PJ, Kavanaugh TE, Bedingfield SK, Mcintyre JO, Milad M, Aleem AM, Coffey RJ, Duvall CL, Marnett LJ. Uddin MJ, et al. Among authors: niitsu h. ACS Med Chem Lett. 2020 Feb 24;11(10):1875-1880. doi: 10.1021/acsmedchemlett.9b00512. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062167 Free PMC article.
Gasdermin C Is Upregulated by Inactivation of Transforming Growth Factor β Receptor Type II in the Presence of Mutated Apc, Promoting Colorectal Cancer Proliferation.
Miguchi M, Hinoi T, Shimomura M, Adachi T, Saito Y, Niitsu H, Kochi M, Sada H, Sotomaru Y, Ikenoue T, Shigeyasu K, Tanakaya K, Kitadai Y, Sentani K, Oue N, Yasui W, Ohdan H. Miguchi M, et al. Among authors: niitsu h. PLoS One. 2016 Nov 11;11(11):e0166422. doi: 10.1371/journal.pone.0166422. eCollection 2016. PLoS One. 2016. PMID: 27835699 Free PMC article.
107 results