Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor

Gastroenterology. 2020 Apr;158(5):1500-1502. doi: 10.1053/j.gastro.2019.12.017. Epub 2019 Dec 19.
No abstract available

Keywords: Colorectal Cancer; EGFR; MM-151; Ménétrier's Disease.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Humanized / pharmacology*
  • Antibodies, Monoclonal, Humanized / therapeutic use
  • Antibodies, Neutralizing / pharmacology*
  • Antibodies, Neutralizing / therapeutic use
  • Azoxymethane / toxicity
  • Carcinogens / toxicity
  • Cells, Cultured
  • Colonic Neoplasms / chemically induced
  • Colonic Neoplasms / drug therapy*
  • Colonic Neoplasms / immunology
  • Colonic Neoplasms / pathology
  • Dextran Sulfate / toxicity
  • Disease Models, Animal
  • ErbB Receptors / genetics
  • ErbB Receptors / immunology*
  • Gastritis, Hypertrophic / drug therapy*
  • Gastritis, Hypertrophic / genetics
  • Gastritis, Hypertrophic / immunology
  • Gastritis, Hypertrophic / pathology
  • Genes, Reporter / genetics
  • Genes, Reporter / immunology
  • Hepatocytes
  • Humans
  • Mice
  • Mice, Transgenic
  • Primary Cell Culture

Substances

  • Antibodies, Monoclonal, Humanized
  • Antibodies, Neutralizing
  • Carcinogens
  • MM-151
  • Dextran Sulfate
  • EGFR protein, mouse
  • ErbB Receptors
  • Azoxymethane