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Increased hexosamine biosynthetic pathway flux dedifferentiates INS-1E cells and murine islets by an extracellular signal-regulated kinase (ERK)1/2-mediated signal transmission pathway.
Lombardi A, Ulianich L, Treglia AS, Nigro C, Parrillo L, Lofrumento DD, Nicolardi G, Garbi C, Beguinot F, Miele C, Di Jeso B. Lombardi A, et al. Among authors: nigro c. Diabetologia. 2012 Jan;55(1):141-53. doi: 10.1007/s00125-011-2315-1. Epub 2011 Oct 18. Diabetologia. 2012. PMID: 22006246
Peroxisome proliferator-activated receptor-γ activation enhances insulin-stimulated glucose disposal by reducing ped/pea-15 gene expression in skeletal muscle cells: evidence for involvement of activator protein-1.
Ungaro P, Mirra P, Oriente F, Nigro C, Ciccarelli M, Vastolo V, Longo M, Perruolo G, Spinelli R, Formisano P, Miele C, Beguinot F. Ungaro P, et al. Among authors: nigro c. J Biol Chem. 2012 Dec 14;287(51):42951-61. doi: 10.1074/jbc.M112.406637. Epub 2012 Oct 26. J Biol Chem. 2012. PMID: 23105093 Free PMC article.
Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo.
Nigro C, Raciti GA, Leone A, Fleming TH, Longo M, Prevenzano I, Fiory F, Mirra P, D'Esposito V, Ulianich L, Nawroth PP, Formisano P, Beguinot F, Miele C. Nigro C, et al. Diabetologia. 2014 Jul;57(7):1485-94. doi: 10.1007/s00125-014-3243-7. Epub 2014 Apr 24. Diabetologia. 2014. PMID: 24759959
256 results