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Long-term platinum-based drug accumulation in cancer-associated fibroblasts promotes colorectal cancer progression and resistance to therapy.
Linares J, Sallent-Aragay A, Badia-Ramentol J, Recort-Bascuas A, Méndez A, Manero-Rupérez N, Re DL, Rivas EI, Guiu M, Zwick M, Iglesias M, Martinez-Ciarpaglini C, Tarazona N, Varese M, Hernando-Momblona X, Cañellas-Socias A, Orrillo M, Garrido M, Saoudi N, Elez E, Navarro P, Tabernero J, Gomis RR, Batlle E, Pisonero J, Cervantes A, Montagut C, Calon A. Linares J, et al. Among authors: navarro p. Nat Commun. 2023 Feb 10;14(1):746. doi: 10.1038/s41467-023-36334-1. Nat Commun. 2023. PMID: 36765091 Free PMC article.
Key contribution of CPEB4-mediated translational control to cancer progression.
Ortiz-Zapater E, Pineda D, Martínez-Bosch N, Fernández-Miranda G, Iglesias M, Alameda F, Moreno M, Eliscovich C, Eyras E, Real FX, Méndez R, Navarro P. Ortiz-Zapater E, et al. Among authors: navarro p. Nat Med. 2011 Dec 4;18(1):83-90. doi: 10.1038/nm.2540. Nat Med. 2011. PMID: 22138752
Galectin-1 drives pancreatic carcinogenesis through stroma remodeling and Hedgehog signaling activation.
Martínez-Bosch N, Fernández-Barrena MG, Moreno M, Ortiz-Zapater E, Munné-Collado J, Iglesias M, André S, Gabius HJ, Hwang RF, Poirier F, Navas C, Guerra C, Fernández-Zapico ME, Navarro P. Martínez-Bosch N, et al. Among authors: navarro p. Cancer Res. 2014 Jul 1;74(13):3512-24. doi: 10.1158/0008-5472.CAN-13-3013. Epub 2014 May 8. Cancer Res. 2014. PMID: 24812270 Free PMC article.
Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor-stroma crosstalk.
Orozco CA, Martinez-Bosch N, Guerrero PE, Vinaixa J, Dalotto-Moreno T, Iglesias M, Moreno M, Djurec M, Poirier F, Gabius HJ, Fernandez-Zapico ME, Hwang RF, Guerra C, Rabinovich GA, Navarro P. Orozco CA, et al. Among authors: navarro p. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3769-E3778. doi: 10.1073/pnas.1722434115. Epub 2018 Apr 3. Proc Natl Acad Sci U S A. 2018. PMID: 29615514 Free PMC article.
Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis.
Martínez-Bosch N, Cristóbal H, Iglesias M, Gironella M, Barranco L, Visa L, Calafato D, Jiménez-Parrado S, Earl J, Carrato A, Manero-Rupérez N, Moreno M, Morales A, Guerra C, Navarro P, García de Frutos P. Martínez-Bosch N, et al. Among authors: navarro p. EBioMedicine. 2022 Jan;75:103797. doi: 10.1016/j.ebiom.2021.103797. Epub 2021 Dec 29. EBioMedicine. 2022. PMID: 34973624 Free PMC article.
Peptides against Low Density Lipoprotein (LDL) Aggregation Inhibit Intracellular Cholesteryl Ester Loading and Proliferation of Pancreatic Tumor Cells.
Benitez-Amaro A, Martínez-Bosch N, Manero-Rupérez N, Claudi L, La Chica Lhoëst MT, Soler M, Ros-Blanco L, Navarro P, Llorente-Cortés V. Benitez-Amaro A, et al. Among authors: navarro p. Cancers (Basel). 2022 Feb 11;14(4):890. doi: 10.3390/cancers14040890. Cancers (Basel). 2022. PMID: 35205638 Free PMC article.
923 results