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Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
Herold T, Schneider S, Metzeler KH, Neumann M, Hartmann L, Roberts KG, Konstandin NP, Greif PA, Bräundl K, Ksienzyk B, Huk N, Schneider I, Zellmeier E, Jurinovic V, Mansmann U, Hiddemann W, Mullighan CG, Bohlander SK, Spiekermann K, Hoelzer D, Brüggemann M, Baldus CD, Dreyling M, Gökbuget N. Herold T, et al. Among authors: mullighan cg. Haematologica. 2017 Jan;102(1):130-138. doi: 10.3324/haematol.2015.136366. Epub 2016 Aug 25. Haematologica. 2017. PMID: 27561722 Free PMC article.
Genomic assessment of pediatric acute leukemia.
Mullighan CG, Flotho C, Downing JR. Mullighan CG, et al. Cancer J. 2005 Jul-Aug;11(4):268-82. doi: 10.1097/00130404-200507000-00003. Cancer J. 2005. PMID: 16197717 Review.
Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia.
Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR. Mullighan CG, et al. Nature. 2007 Apr 12;446(7137):758-64. doi: 10.1038/nature05690. Nature. 2007. PMID: 17344859
Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia.
Mullighan CG, Su X, Zhang J, Radtke I, Phillips LA, Miller CB, Ma J, Liu W, Cheng C, Schulman BA, Harvey RC, Chen IM, Clifford RJ, Carroll WL, Reaman G, Bowman WP, Devidas M, Gerhard DS, Yang W, Relling MV, Shurtleff SA, Campana D, Borowitz MJ, Pui CH, Smith M, Hunger SP, Willman CL, Downing JR; Children's Oncology Group. Mullighan CG, et al. N Engl J Med. 2009 Jan 29;360(5):470-80. doi: 10.1056/NEJMoa0808253. Epub 2009 Jan 7. N Engl J Med. 2009. PMID: 19129520 Free PMC article.
Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia.
Coustan-Smith E, Mullighan CG, Onciu M, Behm FG, Raimondi SC, Pei D, Cheng C, Su X, Rubnitz JE, Basso G, Biondi A, Pui CH, Downing JR, Campana D. Coustan-Smith E, et al. Among authors: mullighan cg. Lancet Oncol. 2009 Feb;10(2):147-56. doi: 10.1016/S1470-2045(08)70314-0. Epub 2009 Jan 13. Lancet Oncol. 2009. PMID: 19147408 Free PMC article.
JAK mutations in high-risk childhood acute lymphoblastic leukemia.
Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL. Mullighan CG, et al. Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9414-8. doi: 10.1073/pnas.0811761106. Epub 2009 May 22. Proc Natl Acad Sci U S A. 2009. PMID: 19470474 Free PMC article.
Genomic analysis of acute leukemia.
Mullighan CG. Mullighan CG. Int J Lab Hematol. 2009 Aug;31(4):384-97. doi: 10.1111/j.1751-553X.2009.01167.x. Epub 2009 May 18. Int J Lab Hematol. 2009. PMID: 19486196 Review.
371 results