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Streptococcus pneumoniae pilus subunits protect mice against lethal challenge.
Gianfaldoni C, Censini S, Hilleringmann M, Moschioni M, Facciotti C, Pansegrau W, Masignani V, Covacci A, Rappuoli R, Barocchi MA, Ruggiero P. Gianfaldoni C, et al. Among authors: moschioni m. Infect Immun. 2007 Feb;75(2):1059-62. doi: 10.1128/IAI.01400-06. Epub 2006 Dec 4. Infect Immun. 2007. PMID: 17145945 Free PMC article.
A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells.
Bagnoli F, Moschioni M, Donati C, Dimitrovska V, Ferlenghi I, Facciotti C, Muzzi A, Giusti F, Emolo C, Sinisi A, Hilleringmann M, Pansegrau W, Censini S, Rappuoli R, Covacci A, Masignani V, Barocchi MA. Bagnoli F, et al. Among authors: moschioni m. J Bacteriol. 2008 Aug;190(15):5480-92. doi: 10.1128/JB.00384-08. Epub 2008 May 30. J Bacteriol. 2008. PMID: 18515415 Free PMC article.
Sortase A confers protection against Streptococcus pneumoniae in mice.
Gianfaldoni C, Maccari S, Pancotto L, Rossi G, Hilleringmann M, Pansegrau W, Sinisi A, Moschioni M, Masignani V, Rappuoli R, Del Giudice G, Ruggiero P. Gianfaldoni C, et al. Among authors: moschioni m. Infect Immun. 2009 Jul;77(7):2957-61. doi: 10.1128/IAI.01516-08. Epub 2009 May 11. Infect Immun. 2009. PMID: 19433540 Free PMC article.
Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain.
Gentile MA, Melchiorre S, Emolo C, Moschioni M, Gianfaldoni C, Pancotto L, Ferlenghi I, Scarselli M, Pansegrau W, Veggi D, Merola M, Cantini F, Ruggiero P, Banci L, Masignani V. Gentile MA, et al. Among authors: moschioni m. J Biol Chem. 2011 Apr 22;286(16):14588-97. doi: 10.1074/jbc.M110.202739. Epub 2011 Mar 2. J Biol Chem. 2011. PMID: 21367860 Free PMC article.
The Streptococcus pneumoniae pilus-1 displays a biphasic expression pattern.
De Angelis G, Moschioni M, Muzzi A, Pezzicoli A, Censini S, Delany I, Lo Sapio M, Sinisi A, Donati C, Masignani V, Barocchi MA. De Angelis G, et al. Among authors: moschioni m. PLoS One. 2011;6(6):e21269. doi: 10.1371/journal.pone.0021269. Epub 2011 Jun 22. PLoS One. 2011. PMID: 21731688 Free PMC article.
RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies.
Harfouche C, Filippini S, Gianfaldoni C, Ruggiero P, Moschioni M, Maccari S, Pancotto L, Arcidiacono L, Galletti B, Censini S, Mori E, Giuliani M, Facciotti C, Cartocci E, Savino S, Doro F, Pallaoro M, Nocadello S, Mancuso G, Haston M, Goldblatt D, Barocchi MA, Pizza M, Rappuoli R, Masignani V. Harfouche C, et al. Among authors: moschioni m. Infect Immun. 2012 Jan;80(1):451-60. doi: 10.1128/IAI.05780-11. Epub 2011 Nov 14. Infect Immun. 2012. PMID: 22083702 Free PMC article.
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