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Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.
Rohwer N, Jumpertz S, Erdem M, Egners A, Warzecha KT, Fragoulis A, Kühl AA, Kramann R, Neuss S, Rudolph I, Endermann T, Zasada C, Apostolova I, Gerling M, Kempa S, Hughes R, Lewis CE, Brenner W, Malinowski MB, Stockmann M, Schomburg L, Faller W, Sansom OJ, Tacke F, Morkel M, Cramer T. Rohwer N, et al. Among authors: morkel m. Oncogene. 2019 Jul;38(28):5670-5685. doi: 10.1038/s41388-019-0816-4. Epub 2019 May 1. Oncogene. 2019. PMID: 31043706 Free article.
Single-cell RNA sequencing reveals distinct tumor microenvironmental patterns in lung adenocarcinoma.
Bischoff P, Trinks A, Obermayer B, Pett JP, Wiederspahn J, Uhlitz F, Liang X, Lehmann A, Jurmeister P, Elsner A, Dziodzio T, Rückert JC, Neudecker J, Falk C, Beule D, Sers C, Morkel M, Horst D, Blüthgen N, Klauschen F. Bischoff P, et al. Among authors: morkel m. Oncogene. 2021 Dec;40(50):6748-6758. doi: 10.1038/s41388-021-02054-3. Epub 2021 Oct 18. Oncogene. 2021. PMID: 34663877 Free PMC article.
Wnt and BMP signals control intestinal adenoma cell fates.
Farrall AL, Riemer P, Leushacke M, Sreekumar A, Grimm C, Herrmann BG, Morkel M. Farrall AL, et al. Among authors: morkel m. Int J Cancer. 2012 Nov 15;131(10):2242-52. doi: 10.1002/ijc.27500. Epub 2012 Mar 28. Int J Cancer. 2012. PMID: 22344573 Free article.
Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium.
Brandt R, Sell T, Lüthen M, Uhlitz F, Klinger B, Riemer P, Giesecke-Thiel C, Schulze S, El-Shimy IA, Kunkel D, Fauler B, Mielke T, Mages N, Herrmann BG, Sers C, Blüthgen N, Morkel M. Brandt R, et al. Among authors: morkel m. Nat Commun. 2019 Jul 2;10(1):2919. doi: 10.1038/s41467-019-10954-y. Nat Commun. 2019. PMID: 31266962 Free PMC article.
Identification of Y-box binding protein 1 as a core regulator of MEK/ERK pathway-dependent gene signatures in colorectal cancer cells.
Jürchott K, Kuban RJ, Krech T, Blüthgen N, Stein U, Walther W, Friese C, Kiełbasa SM, Ungethüm U, Lund P, Knösel T, Kemmner W, Morkel M, Fritzmann J, Schlag PM, Birchmeier W, Krueger T, Sperling S, Sers C, Royer HD, Herzel H, Schäfer R. Jürchott K, et al. Among authors: morkel m. PLoS Genet. 2010 Dec 2;6(12):e1001231. doi: 10.1371/journal.pgen.1001231. PLoS Genet. 2010. PMID: 21170361 Free PMC article.
Mitogen-activated protein kinase activity drives cell trajectories in colorectal cancer.
Uhlitz F, Bischoff P, Peidli S, Sieber A, Trinks A, Lüthen M, Obermayer B, Blanc E, Ruchiy Y, Sell T, Mamlouk S, Arsie R, Wei TT, Klotz-Noack K, Schwarz RF, Sawitzki B, Kamphues C, Beule D, Landthaler M, Sers C, Horst D, Blüthgen N, Morkel M. Uhlitz F, et al. Among authors: morkel m. EMBO Mol Med. 2021 Oct 7;13(10):e14123. doi: 10.15252/emmm.202114123. Epub 2021 Aug 19. EMBO Mol Med. 2021. PMID: 34409732 Free PMC article.
43 results