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FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice.
Misaka T, Murakawa T, Nishida K, Omori Y, Taneike M, Omiya S, Molenaar C, Uno Y, Yamaguchi O, Takeda J, Shah AM, Otsu K. Misaka T, et al. Among authors: molenaar c. J Mol Cell Cardiol. 2018 Jan;114:93-104. doi: 10.1016/j.yjmcc.2017.11.004. Epub 2017 Nov 10. J Mol Cell Cardiol. 2018. PMID: 29129702 Free PMC article.
Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling.
Santos CX, Hafstad AD, Beretta M, Zhang M, Molenaar C, Kopec J, Fotinou D, Murray TV, Cobb AM, Martin D, Zeh Silva M, Anilkumar N, Schröder K, Shanahan CM, Brewer AC, Brandes RP, Blanc E, Parsons M, Belousov V, Cammack R, Hider RC, Steiner RA, Shah AM. Santos CX, et al. Among authors: molenaar c. EMBO J. 2016 Feb 1;35(3):319-34. doi: 10.15252/embj.201592394. Epub 2016 Jan 7. EMBO J. 2016. PMID: 26742780 Free PMC article.
Role of miR-195 in aortic aneurysmal disease.
Zampetaki A, Attia R, Mayr U, Gomes RS, Phinikaridou A, Yin X, Langley SR, Willeit P, Lu R, Fanshawe B, Fava M, Barallobre-Barreiro J, Molenaar C, So PW, Abbas A, Jahangiri M, Waltham M, Botnar R, Smith A, Mayr M. Zampetaki A, et al. Among authors: molenaar c. Circ Res. 2014 Oct 24;115(10):857-66. doi: 10.1161/CIRCRESAHA.115.304361. Epub 2014 Sep 8. Circ Res. 2014. PMID: 25201911
Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries.
Suna G, Wojakowski W, Lynch M, Barallobre-Barreiro J, Yin X, Mayr U, Baig F, Lu R, Fava M, Hayward R, Molenaar C, White SJ, Roleder T, Milewski KP, Gasior P, Buszman PP, Buszman P, Jahangiri M, Shanahan CM, Hill J, Mayr M. Suna G, et al. Among authors: molenaar c. Circulation. 2018 Jan 9;137(2):166-183. doi: 10.1161/CIRCULATIONAHA.116.023381. Epub 2017 Oct 13. Circulation. 2018. PMID: 29030347 Free PMC article.
Nox4 regulates InsP3 receptor-dependent Ca2+ release into mitochondria to promote cell survival.
Beretta M, Santos CX, Molenaar C, Hafstad AD, Miller CC, Revazian A, Betteridge K, Schröder K, Streckfuß-Bömeke K, Doroshow JH, Fleck RA, Su TP, Belousov VV, Parsons M, Shah AM. Beretta M, et al. Among authors: molenaar c. EMBO J. 2020 Oct 1;39(19):e103530. doi: 10.15252/embj.2019103530. Epub 2020 Aug 10. EMBO J. 2020. PMID: 33001475 Free PMC article.
L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt MR, Patel A, Charras GT, Stramer B, Molenaar C, Tedder TF, Parsons M, Ivetic A. Rzeniewicz K, et al. Among authors: molenaar c. Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):E1461-70. doi: 10.1073/pnas.1417100112. Epub 2015 Mar 9. Proc Natl Acad Sci U S A. 2015. PMID: 25775539 Free PMC article.
Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.
Langley SR, Willeit K, Didangelos A, Matic LP, Skroblin P, Barallobre-Barreiro J, Lengquist M, Rungger G, Kapustin A, Kedenko L, Molenaar C, Lu R, Barwari T, Suna G, Yin X, Iglseder B, Paulweber B, Willeit P, Shalhoub J, Pasterkamp G, Davies AH, Monaco C, Hedin U, Shanahan CM, Willeit J, Kiechl S, Mayr M. Langley SR, et al. Among authors: molenaar c. J Clin Invest. 2017 Apr 3;127(4):1546-1560. doi: 10.1172/JCI86924. Epub 2017 Mar 20. J Clin Invest. 2017. PMID: 28319050 Free PMC article.
77 results