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The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation.
Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, Williamson C, Swanstrom R. Abrahams MR, et al. Among authors: moeser m. Sci Transl Med. 2019 Oct 9;11(513):eaaw5589. doi: 10.1126/scitranslmed.aaw5589. Sci Transl Med. 2019. PMID: 31597754 Free PMC article.
Measuring the contribution of γδ T cells to the persistent HIV reservoir.
James KS, Trumble I, Clohosey ML, Moeser M, Roan NR, Adimora AA, Joseph SB, Archin NM, Hudgens M, Soriano-Sarabia N. James KS, et al. Among authors: moeser m. AIDS. 2020 Mar 1;34(3):363-371. doi: 10.1097/QAD.0000000000002434. AIDS. 2020. PMID: 31764074 Free PMC article.
Near Real-Time Identification of Recent Human Immunodeficiency Virus Transmissions, Transmitted Drug Resistance Mutations, and Transmission Networks by Multiplexed Primer ID-Next-Generation Sequencing in North Carolina.
Zhou S, Sizemore S, Moeser M, Zimmerman S, Samoff E, Mobley V, Frost S, Cressman A, Clark M, Skelly T, Kelkar H, Veluvolu U, Jones C, Eron J, Cohen M, Nelson JAE, Swanstrom R, Dennis AM. Zhou S, et al. Among authors: moeser m. J Infect Dis. 2021 Mar 3;223(5):876-884. doi: 10.1093/infdis/jiaa417. J Infect Dis. 2021. PMID: 32663847 Free PMC article.
The HIV-1 latent reservoir is largely sensitive to circulating T cells.
Warren JA, Zhou S, Xu Y, Moeser MJ, MacMillan DR, Council O, Kirchherr J, Sung JM, Roan NR, Adimora AA, Joseph S, Kuruc JD, Gay CL, Margolis DM, Archin N, Brumme ZL, Swanstrom R, Goonetilleke N. Warren JA, et al. Among authors: moeser mj. Elife. 2020 Oct 6;9:e57246. doi: 10.7554/eLife.57246. Elife. 2020. PMID: 33021198 Free PMC article.
Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size.
Ismail SD, Riou C, Joseph SB, Archin NM, Margolis DM, Perelson AS, Cassidy T, Abrahams MR, Moeser M, Council OD, McKinnon LR, Osman F, Karim QA, Abdool Karim SS, Swanstrom R, Williamson C, Garrett NJ, Burgers WA. Ismail SD, et al. Among authors: moeser m. Clin Infect Dis. 2021 Oct 20;73(8):1528-1531. doi: 10.1093/cid/ciab587. Clin Infect Dis. 2021. PMID: 34181706 Free PMC article.
Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat.
Gay CL, James KS, Tuyishime M, Falcinelli SD, Joseph SB, Moeser MJ, Allard B, Kirchherr JL, Clohosey M, Raines SLM, Montefiori DC, Shen X, Gorelick RJ, Gama L, McDermott AB, Koup RA, Mascola JR, Floris-Moore M, Kuruc JD, Ferrari G, Eron JJ, Archin NM, Margolis DM. Gay CL, et al. Among authors: moeser mj. J Infect Dis. 2022 Mar 2;225(5):856-861. doi: 10.1093/infdis/jiab487. J Infect Dis. 2022. PMID: 34562096 Free PMC article.
Use of Next-Generation Sequencing in a State-Wide Strategy of HIV-1 Surveillance: Impact of the SARS-COV-2 Pandemic on HIV-1 Diagnosis and Transmission.
Zhou S, Long N, Moeser M, Hill CS, Samoff E, Mobley V, Frost S, Bayer C, Kelly E, Greifinger A, Shone S, Glover W, Clark M, Eron J, Cohen M, Swanstrom R, Dennis AM. Zhou S, et al. Among authors: moeser m. J Infect Dis. 2023 Dec 20;228(12):1758-1765. doi: 10.1093/infdis/jiad211. J Infect Dis. 2023. PMID: 37283544
Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy.
Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, Moeser M, Sondgeroth AL, Whitehill GD, Singh V, Dashti A, Smith DM, Eron JJ, Bar KJ, Chahroudi A, Joseph SB, Archin NM, Margolis DM, Jiang G. Tang Y, et al. Among authors: moeser m. J Clin Invest. 2023 Jun 15;133(12):e167417. doi: 10.1172/JCI167417. J Clin Invest. 2023. PMID: 37317962 Free PMC article.
22 results