Mitchell JA - Search Results

1

Enhancers and super-enhancers have an equivalent regulatory role in embryonic stem cells through regulation of single or multiple genes.

Moorthy SD, Davidson S, Shchuka VM, Singh G, Malek-Gilani N, Langroudi L, Martchenko A, So V, Macpherson NN, Mitchell JA. Moorthy SD, et al. Among authors: mitchell ja. Genome Res. 2017 Feb;27(2):246-258. doi: 10.1101/gr.210930.116. Epub 2016 Nov 28. Genome Res. 2017. PMID: 27895109 Free PMC article.

2

Enhancer identification in mouse embryonic stem cells using integrative modeling of chromatin and genomic features.

Chen CY, Morris Q, Mitchell JA. Chen CY, et al. Among authors: mitchell ja. BMC Genomics. 2012 Apr 26;13:152. doi: 10.1186/1471-2164-13-152. BMC Genomics. 2012. PMID: 22537144 Free PMC article.

3

Nuclear organization of RNA polymerase II transcription.

Davidson S, Macpherson N, Mitchell JA. Davidson S, et al. Among authors: mitchell ja. Biochem Cell Biol. 2013 Feb;91(1):22-30. doi: 10.1139/bcb-2012-0059. Epub 2013 Feb 5. Biochem Cell Biol. 2013. PMID: 23442138 Review.

4

A Sox2 distal enhancer cluster regulates embryonic stem cell differentiation potential.

Zhou HY, Katsman Y, Dhaliwal NK, Davidson S, Macpherson NN, Sakthidevi M, Collura F, Mitchell JA. Zhou HY, et al. Among authors: mitchell ja. Genes Dev. 2014 Dec 15;28(24):2699-711. doi: 10.1101/gad.248526.114. Genes Dev. 2014. PMID: 25512558 Free PMC article.

5

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements.

Schoenfelder S, Furlan-Magaril M, Mifsud B, Tavares-Cadete F, Sugar R, Javierre BM, Nagano T, Katsman Y, Sakthidevi M, Wingett SW, Dimitrova E, Dimond A, Edelman LB, Elderkin S, Tabbada K, Darbo E, Andrews S, Herman B, Higgs A, LeProust E, Osborne CS, Mitchell JA, Luscombe NM, Fraser P. Schoenfelder S, et al. Among authors: mitchell ja. Genome Res. 2015 Apr;25(4):582-97. doi: 10.1101/gr.185272.114. Epub 2015 Mar 9. Genome Res. 2015. PMID: 25752748 Free PMC article.

6

Chromatin Dynamics in Lineage Commitment and Cellular Reprogramming.

Shchuka VM, Malek-Gilani N, Singh G, Langroudi L, Dhaliwal NK, Moorthy SD, Davidson S, Macpherson NN, Mitchell JA. Shchuka VM, et al. Among authors: mitchell ja. Genes (Basel). 2015 Jul 17;6(3):641-61. doi: 10.3390/genes6030641. Genes (Basel). 2015. PMID: 26193323 Free PMC article. Review.

7

Generating CRISPR/Cas9 Mediated Monoallelic Deletions to Study Enhancer Function in Mouse Embryonic Stem Cells.

Moorthy SD, Mitchell JA. Moorthy SD, et al. Among authors: mitchell ja. J Vis Exp. 2016 Apr 2;(110):e53552. doi: 10.3791/53552. J Vis Exp. 2016. PMID: 27078492 Free PMC article.

8

KLF4 Nuclear Export Requires ERK Activation and Initiates Exit from Naive Pluripotency.

Dhaliwal NK, Miri K, Davidson S, Tamim El Jarkass H, Mitchell JA. Dhaliwal NK, et al. Among authors: mitchell ja. Stem Cell Reports. 2018 Apr 10;10(4):1308-1323. doi: 10.1016/j.stemcr.2018.02.007. Epub 2018 Mar 8. Stem Cell Reports. 2018. PMID: 29526737 Free PMC article.

9

Variational infinite heterogeneous mixture model for semi-supervised clustering of heart enhancers.

Mehdi TF, Singh G, Mitchell JA, Moses AM. Mehdi TF, et al. Among authors: mitchell ja. Bioinformatics. 2019 Sep 15;35(18):3232-3239. doi: 10.1093/bioinformatics/btz064. Bioinformatics. 2019. PMID: 30753279 Free PMC article.

10

Pluripotency on Lockdown after Deletion of Three Transcription Regulators.

Mitchell JA. Mitchell JA. Cell Stem Cell. 2019 May 2;24(5):681-683. doi: 10.1016/j.stem.2019.04.008. Cell Stem Cell. 2019. PMID: 31051130 Free article.

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