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Proteins inform survival-based differences in patients with glioblastoma.
Stetson LC, Ostrom QT, Schlatzer D, Liao P, Devine K, Waite K, Couce ME, Harris PLR, Kerstetter-Fogle A, Berens ME, Sloan AE, Islam MM, Rajaratnam V, Mirza SP, Chance MR, Barnholtz-Sloan JS. Stetson LC, et al. Among authors: mirza sp. Neurooncol Adv. 2020 Mar 17;2(1):vdaa039. doi: 10.1093/noajnl/vdaa039. eCollection 2020 Jan-Dec. Neurooncol Adv. 2020. PMID: 32642694 Free PMC article.
Development and validation of an LC-MS/MS method for the determination of ARN14988, an acid ceramidase inhibitor, and its application to a pharmacokinetic study in a mouse model.
Rajaratnam V, Islam MM, Kub EF, Rajaratnam S, Kim KB, Rahman MT, Rashid F, Benko AM, Cook JM, Arnold LA, Mirza SP. Rajaratnam V, et al. Among authors: mirza sp. Biomed Chromatogr. 2024 Jan;38(1):e5754. doi: 10.1002/bmc.5754. Epub 2023 Sep 26. Biomed Chromatogr. 2024. PMID: 37750452
Acid ceramidase and its inhibitors: a de novo drug target and a new class of drugs for killing glioblastoma cancer stem cells with high efficiency.
Doan NB, Alhajala H, Al-Gizawiy MM, Mueller WM, Rand SD, Connelly JM, Cochran EJ, Chitambar CR, Clark P, Kuo J, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: mirza sp. Oncotarget. 2017 Nov 7;8(68):112662-112674. doi: 10.18632/oncotarget.22637. eCollection 2017 Dec 22. Oncotarget. 2017. PMID: 29348854 Free PMC article.
Acid ceramidase is a novel drug target for pediatric brain tumors.
Doan NB, Nguyen HS, Montoure A, Al-Gizawiy MM, Mueller WM, Kurpad S, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: mirza sp. Oncotarget. 2017 Apr 11;8(15):24753-24761. doi: 10.18632/oncotarget.15800. Oncotarget. 2017. PMID: 28445970 Free PMC article.
Acid ceramidase confers radioresistance to glioblastoma cells.
Doan NB, Nguyen HS, Al-Gizawiy MM, Mueller WM, Sabbadini RA, Rand SD, Connelly JM, Chitambar CR, Schmainda KM, Mirza SP. Doan NB, et al. Among authors: mirza sp. Oncol Rep. 2017 Oct;38(4):1932-1940. doi: 10.3892/or.2017.5855. Epub 2017 Jul 28. Oncol Rep. 2017. PMID: 28765947 Free PMC article.
Identification of radiation responsive genes and transcriptome profiling via complete RNA sequencing in a stable radioresistant U87 glioblastoma model.
Doan NB, Nguyen HS, Alhajala HS, Jaber B, Al-Gizawiy MM, Ahn EE, Mueller WM, Chitambar CR, Mirza SP, Schmainda KM. Doan NB, et al. Among authors: mirza sp. Oncotarget. 2018 May 4;9(34):23532-23542. doi: 10.18632/oncotarget.25247. eCollection 2018 May 4. Oncotarget. 2018. PMID: 29805753 Free PMC article.
42 results