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Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia.
Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, Eheim AL, Stoeckigt D, Maxcy KL, Cobert JM, Bachand J, Szekely BA, Mukherjee S, Sklar LA, Kotz JD, Clish CB, Sadreyev RI, Clemons PA, Janzer A, Schreiber SL, Scadden DT. Sykes DB, et al. Among authors: mercier fe. Cell. 2016 Sep 22;167(1):171-186.e15. doi: 10.1016/j.cell.2016.08.057. Epub 2016 Sep 15. Cell. 2016. PMID: 27641501 Free PMC article.
AKT/FOXO signaling enforces reversible differentiation blockade in myeloid leukemias.
Sykes SM, Lane SW, Bullinger L, Kalaitzidis D, Yusuf R, Saez B, Ferraro F, Mercier F, Singh H, Brumme KM, Acharya SS, Scholl C, Tothova Z, Attar EC, Fröhling S, DePinho RA, Armstrong SA, Gilliland DG, Scadden DT. Sykes SM, et al. Cell. 2011 Sep 2;146(5):697-708. doi: 10.1016/j.cell.2011.07.032. Cell. 2011. PMID: 21884932 Free PMC article.
Xist RNA is a potent suppressor of hematologic cancer in mice.
Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT. Yildirim E, et al. Among authors: mercier fe. Cell. 2013 Feb 14;152(4):727-42. doi: 10.1016/j.cell.2013.01.034. Cell. 2013. PMID: 23415223 Free PMC article.
SnapShot: The hematopoietic stem cell niche.
Kfoury Y, Mercier F, Scadden DT. Kfoury Y, et al. Cell. 2014 Jul 3;158(1):228-228.e1. doi: 10.1016/j.cell.2014.06.019. Cell. 2014. PMID: 24995988 Free article. No abstract available.
Engineering pulmonary vasculature in decellularized rat and human lungs.
Ren X, Moser PT, Gilpin SE, Okamoto T, Wu T, Tapias LF, Mercier FE, Xiong L, Ghawi R, Scadden DT, Mathisen DJ, Ott HC. Ren X, et al. Among authors: mercier fe. Nat Biotechnol. 2015 Oct;33(10):1097-102. doi: 10.1038/nbt.3354. Epub 2015 Sep 14. Nat Biotechnol. 2015. PMID: 26368048
Proximity-Based Differential Single-Cell Analysis of the Niche to Identify Stem/Progenitor Cell Regulators.
Silberstein L, Goncalves KA, Kharchenko PV, Turcotte R, Kfoury Y, Mercier F, Baryawno N, Severe N, Bachand J, Spencer JA, Papazian A, Lee D, Chitteti BR, Srour EF, Hoggatt J, Tate T, Lo Celso C, Ono N, Nutt S, Heino J, Sipilä K, Shioda T, Osawa M, Lin CP, Hu GF, Scadden DT. Silberstein L, et al. Cell Stem Cell. 2016 Oct 6;19(4):530-543. doi: 10.1016/j.stem.2016.07.004. Epub 2016 Aug 11. Cell Stem Cell. 2016. PMID: 27524439 Free PMC article.
45 results