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A Novel Synthesis of Highly Functionalized Pyridines by a One-Pot, Three-Component Tandem Reaction of Aldehydes, Malononitrile and N-Alkyl-2-cyanoacetamides under Microwave Irradiation.
Molecules. 2018 Mar 9;23(3):619. doi: 10.3390/molecules23030619.
Molecules. 2018.
PMID: 29522435
Free PMC article.
Enaminonitriles in heterocyclic synthesis: a route to 1,3-diaryl-4-aminopyrazole derivatives.
Medrasi HY, Al-Sheikh MA, Salaheldin AM.
Medrasi HY, et al.
Molecules. 2013 Jan 2;18(1):535-44. doi: 10.3390/molecules18010535.
Molecules. 2013.
PMID: 23282539
Free PMC article.
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Synthesis and spectroscopic properties of new azo dyes derived from 3-ethylthio-5-cyanomethyl-4-phenyl-1,2,4-triazole.
Al-Sheikh M, Medrasi HY, Sadek KU, Mekheimer RA.
Al-Sheikh M, et al. Among authors: medrasi hy.
Molecules. 2014 Mar 7;19(3):2993-3003. doi: 10.3390/molecules19032993.
Molecules. 2014.
PMID: 24609019
Free PMC article.
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Naphthyridines part 4: unprecedented synthesis of polyfunctionally substituted benzo[c][2,7]naphthyridines and benzo[c]pyrimido[4,5,6-ij][2,7]naphthyridines with structural analogy to pyrido[4,3,2-mn]acridines present in the marine tetracyclic pyridoacridine alkaloids.
Mekheimer RA, Al-Sheikh MA, Medrasi HY, Bahatheg GA.
Mekheimer RA, et al. Among authors: medrasi hy.
Mol Divers. 2018 Feb;22(1):159-171. doi: 10.1007/s11030-017-9788-x. Epub 2017 Nov 21.
Mol Divers. 2018.
PMID: 29164475
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Advancements in the synthesis of fused tetracyclic quinoline derivatives.
Mekheimer RA, Al-Sheikh MA, Medrasi HY, Sadek KU.
Mekheimer RA, et al. Among authors: medrasi hy.
RSC Adv. 2020 May 27;10(34):19867-19935. doi: 10.1039/d0ra02786c. eCollection 2020 May 26.
RSC Adv. 2020.
PMID: 35520416
Free PMC article.
Review.
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Novel 6,7,8-trihydrobenzo[6',7']cyclohepta[2',1'-e]pyrazolo[2,3-a]pyrimidine derivatives as Topo IIα inhibitors with potential cytotoxic activity.
Farghaly TA, Gaber Abdulwahab H, Medrasi HY, Al-Sheikh MA, Katowah DF, Alsaedi AMR.
Farghaly TA, et al. Among authors: medrasi hy.
Bioorg Chem. 2022 Nov;128:106043. doi: 10.1016/j.bioorg.2022.106043. Epub 2022 Jul 20.
Bioorg Chem. 2022.
PMID: 36058118
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Synthesis of tricyclic and tetracyclic benzo[6,7]cycloheptane derivatives linked morpholine moiety as CDK2 inhibitors.
Farghaly TA, Abbas EMH, Al-Sheikh MA, Medrasi HY, Masaret GS, Pashameah RA, Qurban J, Harras MF.
Farghaly TA, et al. Among authors: medrasi hy.
Drug Dev Res. 2023 Sep;84(6):1127-1141. doi: 10.1002/ddr.22074. Epub 2023 May 12.
Drug Dev Res. 2023.
PMID: 37170788
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