McDonald EF - Search Results

1

CFTR Folding: From Structure and Proteostasis to Cystic Fibrosis Personalized Medicine.

McDonald EF, Meiler J, Plate L. McDonald EF, et al. ACS Chem Biol. 2023 Oct 20;18(10):2128-2143. doi: 10.1021/acschembio.3c00310. Epub 2023 Sep 20. ACS Chem Biol. 2023. PMID: 37730207 Free article. Review.

2

Upgraded molecular models of the human KCNQ1 potassium channel.

Kuenze G, Duran AM, Woods H, Brewer KR, McDonald EF, Vanoye CG, George AL Jr, Sanders CR, Meiler J. Kuenze G, et al. Among authors: mcdonald ef. PLoS One. 2019 Sep 13;14(9):e0220415. doi: 10.1371/journal.pone.0220415. eCollection 2019. PLoS One. 2019. PMID: 31518351 Free PMC article.

3

Comparative multiplexed interactomics of SARS-CoV-2 and homologous coronavirus non-structural proteins identifies unique and shared host-cell dependencies.

Davies JP, Almasy KM, McDonald EF, Plate L. Davies JP, et al. Among authors: mcdonald ef. bioRxiv [Preprint]. 2020 Jul 14:2020.07.13.201517. doi: 10.1101/2020.07.13.201517. bioRxiv. 2020. PMID: 32699849 Free PMC article. Updated. Preprint.

4

Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation.

Kuenze G, Vanoye CG, Desai RR, Adusumilli S, Brewer KR, Woods H, McDonald EF, Sanders CR, George AL Jr, Meiler J. Kuenze G, et al. Among authors: mcdonald ef. Elife. 2020 Oct 23;9:e57680. doi: 10.7554/eLife.57680. Elife. 2020. PMID: 33095155 Free PMC article.

5

Comparative Multiplexed Interactomics of SARS-CoV-2 and Homologous Coronavirus Nonstructural Proteins Identifies Unique and Shared Host-Cell Dependencies.

Davies JP, Almasy KM, McDonald EF, Plate L. Davies JP, et al. Among authors: mcdonald ef. ACS Infect Dis. 2020 Dec 11;6(12):3174-3189. doi: 10.1021/acsinfecdis.0c00500. Epub 2020 Dec 2. ACS Infect Dis. 2020. PMID: 33263384 Free PMC article.

6

Structural Comparative Modeling of Multi-Domain F508del CFTR.

McDonald EF, Woods H, Smith ST, Kim M, Schoeder CT, Plate L, Meiler J. McDonald EF, et al. Biomolecules. 2022 Mar 18;12(3):471. doi: 10.3390/biom12030471. Biomolecules. 2022. PMID: 35327663 Free PMC article.

7

Distinct proteostasis states drive pharmacologic chaperone susceptibility for cystic fibrosis transmembrane conductance regulator misfolding mutants.

McDonald EF, Sabusap CMP, Kim M, Plate L. McDonald EF, et al. Mol Biol Cell. 2022 Jun 1;33(7):ar62. doi: 10.1091/mbc.E21-11-0578. Epub 2022 Apr 7. Mol Biol Cell. 2022. PMID: 35389766 Free PMC article.

8

Benchmarking AlphaFold2 on peptide structure prediction.

McDonald EF, Jones T, Plate L, Meiler J, Gulsevin A. McDonald EF, et al. Structure. 2023 Jan 5;31(1):111-119.e2. doi: 10.1016/j.str.2022.11.012. Epub 2022 Dec 15. Structure. 2023. PMID: 36525975 Free PMC article.

9

Elexacaftor/VX-445-mediated CFTR interactome remodeling reveals differential correction driven by mutation-specific translational dynamics.

Kim M, McDonald EF, Sabusap CMP, Timalsina B, Joshi D, Hong JS, Rab A, Sorscher EJ, Plate L. Kim M, et al. Among authors: mcdonald ef. bioRxiv [Preprint]. 2023 Feb 4:2023.02.04.527134. doi: 10.1101/2023.02.04.527134. bioRxiv. 2023. PMID: 36778339 Free PMC article. Updated. Preprint.

10

Computational modeling and prediction of deletion mutants.

Woods H, Schiano DL, Aguirre JI, Ledwitch KV, McDonald EF, Voehler M, Meiler J, Schoeder CT. Woods H, et al. Among authors: mcdonald ef. Structure. 2023 Jun 1;31(6):713-723.e3. doi: 10.1016/j.str.2023.04.005. Epub 2023 Apr 28. Structure. 2023. PMID: 37119820

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