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EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo-controlled phase 2 clinical trial.
Lancet. 2014 May 10;383(9929):1637-1647. doi: 10.1016/S0140-6736(13)62337-5. Epub 2014 Feb 5.
Lancet. 2014.
PMID: 24507377
Clinical Trial.
Inhibition of destructive autoimmune arthritis in FcgammaRIIa transgenic mice by small chemical entities.
Pietersz GA, Mottram PL, van de Velde NC, Sardjono CT, Esparon S, Ramsland PA, Moloney G, Baell JB, McCarthy TD, Matthews BR, Powell MS, Hogarth PM.
Pietersz GA, et al. Among authors: mccarthy td.
Immunol Cell Biol. 2009 Jan;87(1):3-12. doi: 10.1038/icb.2008.82. Epub 2008 Nov 25.
Immunol Cell Biol. 2009.
PMID: 19030019
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Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model.
Patton DL, Cosgrove Sweeney YT, McCarthy TD, Hillier SL.
Patton DL, et al. Among authors: mccarthy td.
Antimicrob Agents Chemother. 2006 May;50(5):1696-700. doi: 10.1128/AAC.50.5.1696-1700.2006.
Antimicrob Agents Chemother. 2006.
PMID: 16641437
Free PMC article.
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Dendrimers as drugs: discovery and preclinical and clinical development of dendrimer-based microbicides for HIV and STI prevention.
McCarthy TD, Karellas P, Henderson SA, Giannis M, O'Keefe DF, Heery G, Paull JR, Matthews BR, Holan G.
McCarthy TD, et al.
Mol Pharm. 2005 Jul-Aug;2(4):312-8. doi: 10.1021/mp050023q.
Mol Pharm. 2005.
PMID: 16053334
Review.
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SPL7013 gel as a topical microbicide for prevention of vaginal transmission of SHIV89.6P in macaques.
Jiang YH, Emau P, Cairns JS, Flanary L, Morton WR, McCarthy TD, Tsai CC.
Jiang YH, et al. Among authors: mccarthy td.
AIDS Res Hum Retroviruses. 2005 Mar;21(3):207-13. doi: 10.1089/aid.2005.21.207.
AIDS Res Hum Retroviruses. 2005.
PMID: 15795526
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Asymmetric synthesis and applications of beta-amino Weinreb amides: asymmetric synthesis of (S)-coniine.
Burke AJ, Davies SG, Garner AC, McCarthy TD, Roberts PM, Smith AD, Rodriguez-Solla H, Vickers RJ.
Burke AJ, et al. Among authors: mccarthy td.
Org Biomol Chem. 2004 May 7;2(9):1387-94. doi: 10.1039/b402531h. Epub 2004 Apr 5.
Org Biomol Chem. 2004.
PMID: 15105931
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